Isolation and partial characterization of an endogenous inhibitor of ceramide glycosyltransferases from rat brain.
Isolation and partial characterization of an endogenous inhibitor of ceramide glycosyltransferases from rat brain.
复制标题
从大鼠脑中分离和部分表征神经酰胺糖基转移酶的内源性抑制剂。
DOI：
10.1016/s0021-9258(17)38209-1
复制
发表时间：
1978
期刊：
影响因子：
--
通讯作者：
K. Suzuki
中科院分区：
文献类型：
--
作者：
E. Costantino‐Ceccarini;K. Suzuki
A heat-stable factor has been extracted from the microsomal membranes of rat brain that inhibits the activities of rat brain ceramide galactosyl- and glucosyltransferases. It is nondialyzable, susceptible to proteolytic enzymes but resistant to DNase and RNase, and has no effect on lysosomal hydrolytic enzymes. The factor could also be prepared from microsomes of bovine, mouse, and rabbit brains and in much lower concentrations, from systemic organs of rats. This inhibitor might play a role in the regulation of ceramide glycosyltransferases in vivo.
