Study of the Sympathetic Vasoconstrictor Nerves to the Vessels of the Dog Hind Limb
Study of the Sympathetic Vasoconstrictor Nerves to the Vessels of the Dog Hind Limb
复制标题
交感缩血管神经对狗后肢血管的研究
DOI：
10.1161/01.res.26.2.171
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发表时间：
1970
影响因子：
20.1
通讯作者：
David A. Ferguson
中科院分区：
文献类型：
--
作者：
David A. Ferguson
在麻醉犬中，后肢血管的血管收缩神经从 T-10 到 L-4 水平的前脊神经根中离开脊髓。最大血管收缩反应发生在刺激 T-12、T-13 和 L-1 根时；刺激 L-4 尾侧的根时没有发生任何情况。神经首先在L-1或以上进入腰椎旁链；最后一个入口点位于 L-4、L-5 层。 L-1、L-2 和 L-3 水平没有纤维离开腰链。第一个出口点位于 L-4，神经继续离开至 S-1（检查的最尾部点）。对腰链刺激的最大反应是在 L-4、L-5 水平。除了一个例外，对前脊神经根、腰链或交感神经节的电刺激的反应仅限于同侧肢体的血管。在 22 只接受单侧交感神经切除术的狗（L-2 至 L-7）中，反射性地或通过前脊髓根部的电刺激引起后肢血管阻力的变化。结果表明，交感神经切除术后77天，交感神经对后肢阻力血管的控制仍然缺失。
In anesthetized dogs, the vasoconstrictor nerves to the vessels of the hind limb left the spinal cord in the anterior spinal nerve roots from T-10 through L-4 levels. Maximal vasoconstrictor responses occurred on stimulation of the T-12, T-13, and L-l roots; none occurred on stimulation of roots caudal to L-4. The nerves first entered the lumbar paravertebral chain at or above L-1; the last point of entry was at the L-4, L-5 level. No fibers left the lumbar chain at L-1, L-2, and L-3 levels. The first point of exit was at L-4, and nerves continued to leave as far distal as S-1, The most caudal point examined. The maximal response to stimulation of the lumbar chain was at the L-4, L-5 level. With a single exception, the responses to electric stimulation of the anterior spinal nerve roots, lumbar chain, or sympathetic ganglia were confined to the vessels of the ipsilateral limb. In 22 dogs with unilateral sympathectomy (L-2 through L-7), changes in hind-limb vascular resistance were induced reflexly or by electric stimulation of the anterior spinal roots. The results indicated that sympathetic control of the resistance vessels of the hind limb was still absent 77 days after sympathectomy.