FragmentationAnalyzer: An open-source tool to analyze MS/MS fragmentation data
FragmentationAnalyzer: An open-source tool to analyze MS/MS fragmentation data
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DOI：
10.1002/pmic.200900681
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发表时间：
2010-03-01
期刊：
影响因子：
3.4
通讯作者：
Martens, Lennart
中科院分区：
文献类型：
--
作者：
Barsnes, Harald;Eidhammer, Ingvar;Martens, Lennart
对MS/MS中碎片化过程的透彻理解可以成为评估所得肽和蛋白质鉴定的有力工具。我们在这里介绍免费提供的开源FragmentationAnalyzer工具（http：//fragmentation-analyzer. googlecode.com），这使得使用一组常见的肽特性来分析特定类型的鉴定肽的大型MS/MS数据集变得简单。这使得能够检测与特定仪器相关或由于翻译后修饰的存在而导致的片段化模式细微差别。
A thorough understanding of the fragmentation processes in MS/MS can be a powerful tool in assessing the resulting peptide and protein identifications. We here present the freely available, open-source FragmentationAnalyzer tool (http://fragmentation-analyzer. googlecode.com) that makes it straightforward to analyze large MS/MS data sets for specific types of identified peptides, using a common set of peptide properties. This enables the detection of fragmentation pattern nuances related to specific instruments or due to the presence of post-translational modifications.