Propagation based differential phase contrast imaging and tomography of murine tissue with a laser plasma x-ray source
Propagation based differential phase contrast imaging and tomography of murine tissue with a laser plasma x-ray source
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DOI：
10.1063/1.2802728
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发表时间：
2007-10
影响因子：
4
通讯作者：
C. Laperle;P. Wintermeyer;J. Wands;D. Shi;M. Anastasio;Xiaodi Li;B. Ahr;G. Diebold;C. Rose-Petruck
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文献类型：
--
作者：
C. Laperle;P. Wintermeyer;J. Wands;D. Shi;M. Anastasio;Xiaodi Li;B. Ahr;G. Diebold;C. Rose-Petruck
超快，激光驱动的X射线源与液体汞目标已被用于相衬成像的切除小鼠肝脏和计算机断层扫描的电子元件。在5kHz重复频率下发射的X射线谱与2.5W、30kV钨阳极微焦点X射线管的X射线谱相似。切除肝脏的图像显示了约20μm空间分辨率的静脉网络。在重建时转移到正交横截面的电子部件的断层摄影图像中的相位对比特征以高对比度示出了设备的内部部件。曝光时间在1至3分钟之间，图像中的信噪比足够高。
An ultrafast, laser-driven x-ray source with a liquid mercury target has been used for phase contrast imaging of an excised murine liver and for computed tomography of an electronic component. The x-ray spectrum emitted at 5kHz repetition rate is found to be similar to that of a 2.5W, 30kV microfocus x-ray tube with a tungsten anode. The images of the excised liver show the venous network with approximately 20μm spatial resolution. Phase contrast features in the tomographic images of the electronic component, transferred to the orthogonal cross sections upon reconstruction, show the internal components of the device with high contrast. Adequate signal-to-noise ratios in the images were achieved with exposure times between 1 and 3min.