Paraneoplastic optic neuropathy and cerebellar ataxia with small cell carcinoma of the lung.
Paraneoplastic optic neuropathy and cerebellar ataxia with small cell carcinoma of the lung.
复制标题
副肿瘤性视神经病变和小脑性共济失调伴小细胞肺癌。
DOI：
10.1097/00041327-200109000-00002
复制
发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Newman,NJ
中科院分区：
文献类型：
--
作者：
Thambisetty,MR;Scherzer,CR;Yu,Z;Lennon,VA;Newman,NJ
Bilateral optic neuropathy and subacute cerebellar ataxia were manifestations of a paraneoplastic neurologic disorder in a woman found to have small cell carcinoma of the lung. Serologic tests revealed a neuronal autoantibody specific for CRMP-5, a 62-kd member of the collapsin response-mediating protein family. Unexplained optic neuropathy in the setting of subacute cerebellar ataxia should cause suspicion of a paraneoplastic disorder and prompt testing for this autoantibody, especially in patients at risk for lung carcinoma.
