Enhancing Quantum Dots for Bioimaging using Advanced Surface Chemistry and Advanced Optical Microscopy: Application to Silicon Quantum Dots (SiQDs)
Enhancing Quantum Dots for Bioimaging using Advanced Surface Chemistry and Advanced Optical Microscopy: Application to Silicon Quantum Dots (SiQDs)
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DOI：
10.1002/adma.201503223
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发表时间：
2015-10-28
影响因子：
29.4
通讯作者：
Gooding, J. Justin
中科院分区：
文献类型：
--
作者：
Cheng, Xiaoyu;Hinde, Elizabeth;Gooding, J. Justin
在生物成像的背景下，荧光寿命成像显微镜成功地展示了表面修饰的纳米晶硅量子点的单光子和双光子情况。该技术与福斯特共振能量转移研究相结合，进一步证明了纳米颗粒的颜色是通过使用有机染料受体直接共轭到纳米颗粒表面来调节的。
Fluorescence lifetime imaging microscopy is successfully demonstrated in both one-and two-photon cases with surface modified, nanocrystalline silicon quantum dots in the context of bioimaging. The technique is further demonstrated in combination with Forster resonance energy transfer studies where the color of the nanoparticles is tuned by using organic dye acceptors directly conjugated onto the nanoparticle surface.