A new mutation in the mouse - Affecting spinal column and urogenital system
A new mutation in the mouse - Affecting spinal column and urogenital system
复制标题
DOI：
10.1093/oxfordjournals.jhered.a104924
复制
发表时间：
1940-01-01
影响因子：
3.1
通讯作者：
Bryson, V
中科院分区：
文献类型：
--
作者：
Dunn, LC;Schofnheimer, SG;Bryson, V
报道了一种新的突变（SD），该突变在杂合条件下产生短尾或句号，脊柱的异常，肾脏缺陷并降低出生后的生存能力。在纯合条件下，它完全是致命的，年轻人出生于正常的比例（152 SD，328 SD，328 SD X，142 x X），但在24小时内死亡。出生。同型旋律是尾鼠，有脊柱裂，缺乏肾脏和外生殖器。 Bagg Inbrod储备的基因增强了Hetrozygous条件的影响，因此现在类似于主要的致命。给出的数据表明，SD独立于另一个短尾突变t和主要的Caracul CA进行分离。
A new mutation (Sd) is reported which in heterozygous condition produces a short-tail or taillessness, abnormalities of the spinal column, defects of the kidneys and lowered viability after birth. In homozygous condition it is entirely lethal, the young being born in normal proportion (152 Sd Sd, 328 Sd x, 142 x x) but dying within 24 hrs. of birth. The homo-zygotes are tailless, have spina bifida, and lack kidneys and external genitalia. The effect of the hetrozygous condition was enhanced by the genes of the Bagg inbred stock so that it now resembles a dominant lethal. Data given indicate that Sd segregates independently of another short-tailed mutation T, and of the dominant Caracul Ca.