Biometric Features of Peripapillary Atrophy Beta in Eyes with High Myopia
Biometric Features of Peripapillary Atrophy Beta in Eyes with High Myopia
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DOI：
10.1167/iovs.11-7580
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发表时间：
2011-08-01
影响因子：
4.4
通讯作者：
Yoshimura, Nagahisa
中科院分区：
文献类型：
--
作者：
Nonaka, Atsushi;Hangai, Masanori;Yoshimura, Nagahisa
目的。采用同步共聚焦扫描激光检眼镜（cSLO）和增强光谱域光学相干断层扫描（SD-OCT）技术评价高度近视眼的乳头周围萎缩β (ppa - β)特征。作者回顾性分析61只高度近视（>= -6.0D）眼，无近视视网膜病变。使用cSLO眼底图像测量从中央凹中心到ppa - β区颞缘和鼻缘的距离；水平横截面SD-OCT图像，以确定内丛状层（IPL）在ppa - β区内终止的位置；和a型超声，测量轴向长度。从中央凹中心到ppa - β区颞缘的距离（2.68 ~ 4.39 mm）与ppa - β的周向范围相关（P < 0.001, r = -0.49）。中央凹中心到鼻缘的距离（3.41 ~ 5.60 mm）与视盘卵形指数（P < 0.001, r = -0.51）和视盘轴向长度（P < 0.05, r = 0.26）相关。ppa - β区宽度（0.20 ~ 2.05 mm）与ppa - β周向范围（P < 0.001, r = 0.42）、视盘卵形指数（P < 0.001, r = -0.68）、视盘轴向长度（P < 0.05, r = 0.32）相关。当ppa - β环向范围较大时，IPL终止区明显靠近视盘（P < 0.01, r = 0.36）。高度近视眼ppa - β生物特征的个体间差异与眼轴长、盘椭圆形程度和周向范围有不同的相关性。（Invest Ophthalmol Vis Sci. 2011; 52: 6706-6713） DOI: 10.1167/iovs.11-7580
PURPOSE. To evaluate peripapillary atrophy beta (PPA-beta) characteristics in highly myopic eyes, using simultaneous confocal scanning laser ophthalmoscopy (cSLO) and enhanced spectraldomain optical coherence tomography (SD-OCT).METHODS. The authors retrospectively analyzed 61 highly myopic (>= -6.0D) eyes without myopic retinopathy. cSLO fundus images were used to measure the distances from the foveal center to the temporal and nasal margins of the PPA-beta zone; horizontal cross-sectional SD-OCT images, to determine the position where the inner plexiform layer (IPL) terminates within the PPA-beta zone; and A-mode ultrasonography, to measure axial length.RESULTS. The distance from the foveal center to the PPA-beta zone temporal margin (2.68-4.39 mm) correlated with the circumferential extent of PPA-beta (P < 0.001, r = -0.49). The distance from the foveal center to the nasal margin (3.41-5.60 mm) correlated with the ovality index of the optic disc (P < 0.001, r = -0.51) and with the axial length (P < 0.05, r = 0.26). PPA-beta zone width (0.20 -2.05 mm) correlated with the circumferential extent of PPA-beta (P < 0.001, r = 0.42), ovality index of the optic disc (P < 0.001, r = -0.68), and axial length (P < 0.05, r = 0.32). The IPL termination within the PPA-beta zone was significantly closer to the optic disc when the circumferential extent of PPA-beta was large (P < 0.01, r = 0.36).CONCLUSIONS. Interindividual variations in biometric features of PPA-beta in highly myopic eyes showed different associations with axial length, degree of disc ovality, and circumferential extent of PPA-beta. (Invest Ophthalmol Vis Sci. 2011; 52: 6706-6713) DOI: 10.1167/iovs.11-7580