Modelling a Multi-Dimensional Model of Memory Performance in Obsessive-Compulsive Disorder: A Multi-Level Meta-Analytic Review.
Modelling a Multi-Dimensional Model of Memory Performance in Obsessive-Compulsive Disorder: A Multi-Level Meta-Analytic Review.
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DOI：
10.31234/osf.io/fk2hx
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发表时间：
2020-03
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影响因子：
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通讯作者：
Ben Harkin;K. Kessler;Sofia Persson;Alan Yates
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作者：
Ben Harkin;K. Kessler;Sofia Persson;Alan Yates
尽管记忆表现是强迫症（OCD）的一个普遍研究方面，但对特定认知因素的作用的连贯和统一的解释仍然难以捉摸。为了解决这一问题，本荟萃分析检查了Harkin和Kessler（2011）执行功能（E）、绑定复杂性（B）和记忆负荷（L）分类系统关于强迫症中受影响与未受影响记忆表现的预测有效性。我们采用多水平荟萃分析方法（Viechtbauer，2010）来适应EBL模型的相互依赖性和效应量的相互依赖性（来自144项研究的305个效应量，包括4424名强迫症患者）。结果显示，EBL模型预测了记忆性能，即，随着EBL需求的增加，强迫症患者在记忆任务中的表现逐渐变差。执行功能是EBL对强迫症记忆表现的影响背后的驱动机制，并否定了强迫症患者视觉和语言任务之间的效应大小差异。子任务效应量的比较也与EBL分类的认知参数基本雅阁。我们的结论是，标准化编码的任务沿着个人的认知维度和多层次的荟萃分析提供了一种新的方法来检查多维模型的记忆和认知表现的强迫症和其他疾病。
Even though memory performance is a commonly researched aspect of Obsessive-Compulsive Disorder (OCD), a coherent and unified explanation of the role of specific cognitive factors has remained elusive. To address this, the present meta-analysis examined the predictive validity of Harkin and Kessler’s (2011) Executive Function (E), Binding Complexity (B) and Memory Load (L) Classification System with regards to affected vs. unaffected memory performance in OCD. We employed a multi-level meta-analytic approach (Viechtbauer, 2010) to accommodate the interdependent nature of the EBL model and interdependency of effect sizes (305 effect sizes from 144 studies, including 4424 OCD patients). Results revealed that the EBL model predicted memory performance, i.e., as EBL demand increases, those with OCD performed progressively worse on memory tasks. Executive function was the driving mechanism behind the EBL’s impact on OCD memory performance and negated effect size differences between visual and verbal tasks in those with OCD. Comparisons of sub-task effect sizes were also generally in accord with the cognitive parameters of the EBL taxonomy. We conclude that standardised coding of tasks along individual cognitive dimensions and multi-level meta-analyses provides a new approach to examine multi-dimensional models of memory and cognitive performance in OCD and other disorders.