The RAISE Connection Program: Psychopharmacological Treatment of People With a First Episode of Schizophrenia.
The RAISE Connection Program: Psychopharmacological Treatment of People With a First Episode of Schizophrenia.
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DOI：
10.1176/appi.ps.201500438
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发表时间：
2016-12-01
期刊：
影响因子：
--
通讯作者：
Buchanan RW
中科院分区：
文献类型：
--
作者：
Kreyenbuhl JA;Medoff DR;McEvoy JP;Smith TE;Hackman AL;Nossel IR;Dixon LB;Essock SM;Buchanan RW
目前的研究检查了精神科医生对推荐的一线和二线抗精神病药物时间表（“抗精神病药物时间表”）的依从性，该时间表在两个初始精神分裂症发作后恢复（RAISE）连接计划实施和评估研究诊所中实施。65名首次精神病发作的患者参加了RAISE连接计划诊所。两名精神科医生接受了培训，并根据抗精神病药物治疗计划，就使用共同决策方法处方抗精神病药物进行了持续咨询。从标准化研究评估和图表提取中获得参与者、处方抗精神病药物和完成副作用评估的信息。使用描述性统计来描述抗精神病药物处方和副作用监测模式与抗精神病药物治疗方案一致的程度。超过90%（n=60）的参与者接受了抗精神病药物治疗，并在76%（± 35%）的治疗日接受了药物治疗。77%的受试者接受了至少一种抗精神病药物治疗方案的一线抗精神病药物，20%接受了奥氮平治疗，10%接受了氯氮平试验。关于监测代谢副作用，92%的参与者（n=55）至少记录了一次体重，72%（n=43）至少记录了一次血糖测量，62%（n=37）至少记录了一次血脂。在对照研究的背景下，由专家向精神科医生提供培训和持续的临床监督，并鼓励共同决策，抗精神病药物处方模式密切遵守RAISE连接计划建立的建议。
The current study examined the adherence of psychiatrists to the Schedule of Recommended First and Second Line Antipsychotic Medications (“Antipsychotic Schedule”), which was implemented in two Recovery After an Initial Schizophrenia Episode (RAISE) Connection Program Implementation and Evaluation Study clinics. Sixty-five individuals with a first episode of psychosis were enrolled in the RAISE Connection Program clinics. Two psychiatrists received training and ongoing consultation on using a shared decision-making approach to prescribing antipsychotic medications according to the Antipsychotic Schedule. Information on participants, prescribed antipsychotic medications, and completion of side effects assessments were obtained from standardized research assessments and chart extractions. Descriptive statistics were used to characterize the extent to which patterns of antipsychotic prescribing and side effect monitoring were consistent with the Antipsychotic Schedule. Over 90% (n=60) of participants were prescribed an antipsychotic medication, and received the medication on 76% (± 35%) of the days they were in treatment. Seventy-seven percent of participants were prescribed at least one Antipsychotic Schedule first-line antipsychotic, 20% were prescribed olanzapine, and 10% received a trial of clozapine. Regarding monitoring for metabolic side effects, 92% of participants (n=55) had at least one weight recorded, 72% (n=43) had at least one blood glucose measure recorded, and 62% (n=37) had at least one lipid profile recorded. In the context of a controlled study, in which training and ongoing clinical supervision by experts was provided to psychiatrists and shared decision-making was encouraged, antipsychotic prescribing patterns closely adhered to recommendations established by the RAISE Connection Program.
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影响因子：
168.9
作者：
Kahn, Rene S.;Fleischhacker, W. Wolfgang;Grobbee, Diederick E.
通讯作者：
Grobbee, Diederick E.
影响因子：
3.8
作者：
Deegan, Patricia E.;Drake, Robert E.
通讯作者：
Drake, Robert E.
影响因子：
3.8
作者：
Essock, Susan M.;Goldman, Howard H.;Dixon, Lisa B.
通讯作者：
Dixon, Lisa B.
影响因子：
5.3
作者：
Perkins, Diana O.;Gu, Hongbin;Lieberman, Jeffrey A.
通讯作者：
Lieberman, Jeffrey A.
影响因子：
4.5
作者：
ADDINGTON, D;ADDINGTON, J;SCHISSEL, B
通讯作者：
SCHISSEL, B