Stage progression of congenital cholesteatoma in children
Stage progression of congenital cholesteatoma in children
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DOI：
10.1007/s00405-011-1737-1
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发表时间：
2012-03-01
影响因子：
2.6
通讯作者：
Kim, Chong Sun
中科院分区：
文献类型：
--
作者：
Kim, Young Ho;Yoo, Jae Chul;Kim, Chong Sun
本研究旨在调查各年龄组先天性角化囊肿（CC）儿童的最常见分期，并验证CC类型（“闭合性”角化囊肿和“开放性”浸润型）分期与患者年龄之间的相关性。2004年至2009年诊断为CC的患者（n = 156; 116名男孩和40名女孩;平均年龄5岁5个月;范围12个月-16岁7个月）回顾性入组。根据术前高分辨率颞骨计算机断层扫描和术中发现评估CC的分期和类型。CC的分期采用Potsic分期系统，根据听骨受累和乳突延伸分为四期。这些患者由基于2年间隔划分的组组成。I期的患病率从1-2岁年龄组开始下降。相比之下，III期的患病率从3-4岁年龄组开始增加，IV期的患病率从5-6岁年龄组开始增加。“开放”浸润型CC的患病率从大约7岁开始增加，因此显示出与年龄而不是与分期有一定的相关性。从2岁开始，晚期CC的患病率增加。因此，应重视CC的早期诊断和治疗。
This study aimed to investigate the most prevalent stage in each age-group of children with congenital cholesteatoma (CC) and verify the correlation between the stage and the age of the patients for the type of CC ("closed" keratotic cyst and "open" infiltrative types). Patients diagnosed with CC between 2004 and 2009 (n = 156; 116 boys and 40 girls; mean age, 5 years and 5 months; range, 12 months-16 years and 7 months) were enrolled retrospectively. Assessment of stage and type of CC was performed with preoperative high-resolution temporal bone computed tomography and intraoperative findings. The stage of CC was determined using Potsic's staging system classified into four stages according to ossicular involvement and mastoid extension. The patients consisted of groups divided on the basis of a 2-year interval. The prevalence of stage I began to decline from the age-group of 1-2 years. In contrast, the prevalence of stages III increased from the age-group of 3-4 years and that of stage IV from the age-group 5-6 years. The prevalence of "open" infiltrative type CC increased from approximately the age of 7 years, thus showing some correlation with age but not with stage. The prevalence of CC with the advanced stage increased since the age of 2 years. Therefore, the importance of early diagnosis and treatment of CC should be more emphasized.