Five-dimensional ultrasound system for soft tissue visualization.
Five-dimensional ultrasound system for soft tissue visualization.
复制标题
用于软组织可视化的五维超声系统。
DOI：
10.1007/s11548-015-1277-z
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发表时间：
2015
影响因子：
3
通讯作者：
Boctor,EmadM
中科院分区：
文献类型：
--
作者：
Deshmukh,NishikantP;Caban,JesusJ;Taylor,RussellH;Hager,GregoryD;Boctor,EmadM
提出了一个五维超声（US）系统作为一个实时管道，包括3D b模式数据与3D超声弹性成像（USE）数据的融合，以及这些融合数据的可视化，以及每次连续扫描的实时更新能力。3D b模式数据有助于可视化目标器官的解剖结构，3D弹性成像数据增加了应变信息。方法研究了该系统的可行性，并证明了从采集到可视化的端到端实时系统是可以开发的。我们提出了一个由(a)基于GPU上的归一化互相关（NCC）计算的实时三维弹性成像算法组成的系统；(b)实时三维b模采集和网络传输；(c)三维弹性成像和b模体的扫描转换（如果由四维摆动探针获得）；以及(d)实时融合、可视化和更新3D b模式和3D弹性成像数据的可视化软件。结果与非线程版本相比，我们实现了基于ncc的3D USE的线程版本的速度提高4.45倍。3D扫描转换的最大速度为79卷/秒。在一个幻影中，我们验证了直径2.2厘米的球体扫描的尺寸-转换为b模式体积。此外，我们验证了5D US系统可视化传递函数，并检测了1和2 cm的球形物体（幻像病变）。最后，我们将该系统应用于由三个病变组成的幻体，从周围的幻体背景区域描绘病变。结论5D US系统具有较好的实时性。我们可以用传递函数来区分幻像中的硬区和软区。
PurposeA five-dimensional ultrasound (US) system is proposed as a real-time pipeline involving fusion of 3D B-mode data with the 3D ultrasound elastography (USE) data as well as visualization of these fused data and a real-time update capability over time for each consecutive scan. 3D B-mode data assist in visualizing the anatomy of the target organ, and 3D elastography data adds strain information.MethodsWe investigate the feasibility of such a system and show that an end-to-end real-time system, from acquisition to visualization, can be developed. We present a system that consists of (a) a real-time 3D elastography algorithm based on a normalized cross-correlation (NCC) computation on a GPU; (b) real-time 3D B-mode acquisition and network transfer; (c) scan conversion of 3D elastography and B-mode volumes (if acquired by 4D wobbler probe); and (d) visualization software that fuses, visualizes, and updates 3D B-mode and 3D elastography data in real time.ResultsWe achieved a speed improvement of 4.45-fold for the threaded version of the NCC-based 3D USE versus the non-threaded version. The maximum speed was 79 volumes/s for 3D scan conversion. In a phantom, we validated the dimensions of a 2.2-cm-diameter sphere scan-converted to B-mode volume. Also, we validated the 5D US system visualization transfer function and detected 1- and 2-cm spherical objects (phantom lesion). Finally, we applied the system to a phantom consisting of three lesions to delineate the lesions from the surrounding background regions of the phantom.ConclusionA 5D US system is achievable with real-time performance. We can distinguish between hard and soft areas in a phantom using the transfer functions.