Screening for autism - Agreement with diagnosis
Screening for autism - Agreement with diagnosis
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DOI：
10.1177/1362361306063288
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发表时间：
2006-05-01
期刊：
影响因子：
5.2
通讯作者：
Ho, Helena H.
中科院分区：
文献类型：
--
作者：
Eaves, Linda C.;Wingert, Heather;Ho, Helena H.
用来确定有自闭症谱系障碍风险的幼儿的筛查措施包括修改的幼儿自闭症检查表(M-ChAT)和社交问卷(SCQ)。为了检查这些书面问卷的有效性，父母在孩子在三级自闭症诊所进行诊断评估之前完成了这些问卷。84名2-3岁儿童的父母参加了M-Chat，94名4-6岁儿童的父母参加了SCQ。在这两项指标上，敏感性均高于特异性，阳性预测值为0.63-0.68。假阴性，或筛查漏掉的自闭症儿童，在某种程度上比真阳性的功能更强。与预期相反，将英语作为第二语言的父母的结果更好。在目前的发展阶段，建议将这些工具作为更全面的监测方案的一部分，以确定需要进一步评估的儿童，但不是用来‘筛选’自闭症的可能性。
Screening measures to identify very young children at risk for autism spectrum disorders include the Modified Checklist for Autism in Toddlers (M-CHAT) and the Social Communication Questionnaire (SCQ). To examine the validity of these written questionnaires, parents completed them prior to their child's diagnostic assessment at a tertiary autism clinic. The M-CHAT was given to 84 parents of 2- to 3-year-olds and the SCQ to 94 parents of 4- to 6-year-olds. On both measures sensitivity was higher than specificity with positive predictive values 0.63-0.68. False negatives, or children with autism who were missed by screening, were somewhat higher functioning than true positives. Results were better for parents who spoke English as a second language, contrary to expectations. At this stage of development these tools would be recommended as part of more comprehensive surveillance programmes to identify children in need of further assessment but not to 'screen out' the possibility of autism.