PAPILLARY THYROID CARCINOMAS - MORPHOLOGY AND PROGNOSIS

PAPILLARY THYROID CARCINOMAS - MORPHOLOGY AND PROGNOSIS
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DOI:
10.1007/bf00428498
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发表时间:
1982-01-01
期刊:
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
影响因子:
--
通讯作者:
HEDINGER, CE
HEDINGER, CE
中科院分区:
其他
文献类型:
--
作者:
TSCHOLLDUCOMMUN, J;HEDINGER, CE

文献摘要

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The histological pattern of 169 surgical cases of human papillary thyroid carcinomas were re-examined because of evident differences in the clinical course of these tumors. The material was classified according to precise morphological criteria and matched with a number of clinical and catamnestic data to determine which parameters correspond best with the development of the disease. Although the fate of patients below 50 yr of age is slightly more favorable than that of older subjects, age is not the most important factor. The prognosis correlates significantly better with the initial local extension of the primary tumor (occult, intrathyroid or extrathyroid). This parameter is closely related to the histological pattern of various papillary carcinoma subtypes which were graded according to differentiation. All factors considered, the morphological pattern appears to offer a rewarding approach to the provision of an accurate prognosis.