SOLAR RETINOPATHY Comparison of Optical Coherence Tomography (OCT) and Fluorescein Angiography (FA)
SOLAR RETINOPATHY Comparison of Optical Coherence Tomography (OCT) and Fluorescein Angiography (FA)
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DOI：
10.1097/iae.0b013e3181b0da88
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发表时间：
2009-10-01
影响因子：
3.3
通讯作者：
Sarraf, David
中科院分区：
文献类型：
--
作者：
Jain, Atul;Desai, Rajen U.;Sarraf, David
目的：比较11例（21眼）太阳视网膜病变中央中央凹损伤的光学相干断层扫描和荧光素血管造影。方法：对11例太阳视网膜病变患者进行回顾性观察。进行眼底扩张镜检查、摄影、荧光素血管造影、光学相干断层扫描和Humphrey视野评估。结果：21只眼（11例）均有明显的中央凹病变。受累眼的视力范围为20/25 ~ 20/200。光学相干断层扫描显示，在所有21只受影响的眼睛中，中央凹萎缩与光感受器内外段连接处的特征性缺陷有关，而荧光素血管造影在19只眼睛中发现了典型的窗口缺陷（11例患者中的10例）。中央凹厚度与视力有一定的相关性。结论：荧光素血管造影不能在所有有明确的凝视史和视力丧失的患者中检测到太阳视网膜病变的特征。相反，光学相干断层扫描确实在所有受影响的眼睛中检测到明显的中央凹萎缩和光感受器-视网膜色素上皮交界处的特征性缺陷。光学相干断层扫描提高了对太阳视网膜病变患者中央凹损伤程度和性质的诊断和评估，可能是识别标准荧光素血管造影未检测到的中央凹损伤的重要工具。视网膜29:40 -1345,2009
Purpose: To compare optical coherence tomography with fluorescein angiography in 11 patients (21 eyes) with central foveal damage from solar retinopathy.Methods: Retrospective, observational case series of 11 patients with solar retinopathy. Dilated funduscopic examination was performed as well as photographic, fluorescein angiography, optical coherence tomography, and Humphrey visual field assessment.Results: Significant foveal pathology was identified in each of the 21 eyes (11 patients). Visual acuity in affected eyes ranged from 20/25 to 20/200. Optical coherence tomography demonstrated foveal atrophy associated with a characteristic defect at the level of the inner and outer segment junction of the photoreceptors in all 21 affected eyes, whereas fluorescein angiography identified classic window defects in 19 eyes (10 of 11 patients). There was a modest correlation between foveal thickness and visual acuity.Conclusion: Fluorescein angiography did not detect lesions characteristic of solar retinopathy in all patients with a definitive history of sungazing and visual loss. Conversely, optical coherence tomography did detect significant foveal atrophy in all affected eyes and a characteristic defect at the photoreceptor-retinal pigment epithelium junction. Optical coherence tomography improves the diagnosis and assessment of the degree and nature of foveal damage in patients with solar retinopathy and may be an important tool in identifying foveal damage not detected by standard fluorescein angiography. RETINA 29:1340-1345, 2009