Persistent direction-changing geotropic positional nystagmus
Persistent direction-changing geotropic positional nystagmus
复制标题
DOI：
10.1007/s00405-011-1700-1
复制
发表时间：
2012-03-01
影响因子：
2.6
通讯作者：
Ichijo, Hiroaki
中科院分区：
文献类型：
--
作者：
Ichijo, Hiroaki
这项研究的目的是阐明持续性方向改变的地致性位置性眼球震颤是否包含垂直和扭转分量，并对不对称性进行量化。我们用三维视频眼底照相术分析了四种体位(健耳向下、患耳向下、仰卧、鼻子向下)的眼震。研究对象为18例持续性向心性位置性眼球震颤患者，其中女性16例，男性2例，平均年龄55岁。用红外线摄像机记录眼球震颤，并将结果转换为数字数据。使用ImageJ进行三维视频眼底成像，测量三组分的最大慢相速度(MSV)。位置性眼球震颤不是纯水平的。8例(44%)患者在健康耳垂时有垂直成分(向上)，15例(83%)患者在健康耳垂位置有扭转成分。7例(39%)患者显示垂直部分(向下)，10例(56%)患者在鼻下位显示扭转部分。仰卧位水平分量的均方根均值为9.3A度/S，鼻下位的均方根均值为15.7A度/S，后者明显大于前者(p<；0.05)。仰卧位和鼻子朝下位置的眼球运动不是镜像。这些结果表明，垂直和扭转成分来自水平半规管，水平半规管眼反射受耳石器官输入的影响。
The aims of the study were to clarify whether persistent direction-changing geotropic positional nystagmus contains vertical and torsional components, and to quantify the asymmetry. We analyzed nystagmus in four positions (healthy-ear-down, affected-ear-down, supine, nose-down) using three-dimensional video-oculography. Subjects were 18 patients with persistent direction-changing geotropic positional nystagmus, 16 females and 2 males, with a mean age of 55 years. Nystagmus was recorded using an infrared camera and the findings were converted to digital data. Using ImageJ, we performed three-dimensional video-oculography and measured maximum slow-phase velocity (MSV) of three components. Positional nystagmus was not purely horizontal. Eight (44%) patients revealed a vertical component (upward) and 15 (83%) patients had a torsional component in the healthy-ear-down position. Seven (39%) patients revealed a vertical component (downward) and 10 (56%) patients showed a torsional component in the nose-down position. The mean value of MSV of the horizontal component in the supine position was 9.3A degrees/s and that in the nose-down position was 15.7A degrees/s. The latter was significantly greater than the former (p < 0.05). Eye movements in the supine position and the nose-down position were not mirror images. These results suggest that vertical and torsional components occur from the horizontal semicircular canal, and that horizontal canal ocular reflex is influenced by input from the otolithic organs.