Clinical features of acute retroviral syndrome differ by route of infection but not by gender and age.
Clinical features of acute retroviral syndrome differ by route of infection but not by gender and age.
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急性逆转录病毒综合征的临床特征因感染途径而异，但不因性别和年龄而异。
DOI：
10.1097/00126334-200211010-00007
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Sékaly,Rafick-Pie
中科院分区：
文献类型：
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作者：
Vanhems,Philippe;Routy,Jean-Pierre;Hirschel,Bernard;Baratin,Dominique;Vora,Samir;Maenza,Janine;Carr,Andrew;Trépo,Christian;Touraine,Jean-Louis;Gillibert,René-Pierre;Collier,AnnC;Cooper,DavidA;Vizzard,Jeanette;Sékaly,Rafick-Pie
艾滋病毒疾病进展的速度与急性逆转录病毒综合征（ARS）的严重程度有关。我们按性别、年龄和感染途径对378例登记为ARS的患者进行了临床特征分析，纳入了5项具有相似入组标准的前瞻性队列研究。性别和年龄之间没有明显的差异。与通过性接触（异性恋或同性恋）获得的感染相比，注射吸毒者报告的一些症状较少。这种情况在发热患者中尤为明显(50% vs. 77%, p=。001)，皮疹(21% vs. 51%, p=。001)，咽炎(18% vs. 43%, p=。004)，肌痛(29% vs. 52%, p=。01)。生殖器溃疡只出现在性接触艾滋病毒的情况下。与通过性传播感染艾滋病毒的人相比，注射吸毒者出现或报告出现与急性呼吸道感染相关症状的频率要低。
: The rate of HIV disease progression is associated with the severity of the acute retroviral syndrome (ARS). We explored the clinical features of ARS by gender, age and route of infection among 378 individuals with documented ARS enrolled in 5 prospective cohort studies with similar enrollment criteria. No major differences were detected by gender or by age. Several symptoms were reported less frequently in the injecting drug users as compared with infection acquired through sexual contacts (either heterosexual or homosexual). This was observed in particular for fever (50% vs. 77%, p=. 001), skin rash (21% vs. 51%, p=. 001), pharyngitis (18% vs. 43%, p=. 004), and myalgia (29% vs. 52%, p=. 01). Genital ulcerations were present only in cases of sexual exposure to HIV. Injecting drug users had or reported symptoms associated with the ARS less frequently than persons acquiring HIV via sexual transmission.