Two Arabidopsis homologs of the animal trithorax genes:: a new structural domain is a signature feature of the trithorax gene family
Two Arabidopsis homologs of the animal trithorax genes:: a new structural domain is a signature feature of the trithorax gene family
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DOI：
10.1016/s0378-1119(01)00524-8
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发表时间：
2001-06-27
期刊：
影响因子：
3.5
通讯作者：
Avramova, Z
中科院分区：
文献类型：
--
作者：
Alvarez-Venegas, R;Avramova, Z
两个拟南芥基因已被鉴定为与动物三胸基因同源的植物基因的第一个例子。拟南芥基因高度相似，但显示不同的组织和发育表达模式。其中一种普遍表达，在幼苗中表达水平最高。另一个基因在所有测试组织中活性较低，在成熟叶中不表达，但在根中高度表达。一个新的结构基序共同的所有TRX相关的蛋白质已被确定。这种新的结构元素只在多细胞物种的基因中发现，并且存在于属于三胸家族的所有基因中。沿着SET结构域和PHD指，该新元素是三胸基因家族的标志特征。(C)2001 Elsevier Science B.V.保留所有权利。
Two Arabidopsis genes have been characterized as first examples of plant genes homologous to the animal trithorax genes. The Arabidopsis genes are highly similar but display different tissue and development expression patterns. One of them was ubiquitously expressed, with highest levels registered in young seedlings. The other gene was less active in all tested tissues, was not expressed in mature leaves but was highly expressed in roots. A new structural motif common to all TRX-related proteins has been identified. This new architectural element was found only in genes of multicellular species and is present in all genes belonging to the trithorax family. Along with the SET domain and the PHD fingers, this new element is a signature feature for the trithorax gene family. (C) 2001 Elsevier Science B.V. All rights reserved.