Different dynamics of performance and brain activation in the time course of perceptual learning
Different dynamics of performance and brain activation in the time course of perceptual learning
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DOI：
10.1016/j.neuron.2008.02.034
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发表时间：
2008-03-27
期刊：
影响因子：
16.2
通讯作者：
Sasaki, Yuka
中科院分区：
文献类型：
--
作者：
Yotsumoto, Yuko;Watanabe, Takeo;Sasaki, Yuka
知觉学习被认为是感觉系统中经验依赖可塑性的一种表现，但其潜在的神经机制尚不清楚。在知觉学习过程中，我们测量了视觉任务的动态表现和人类初级视觉皮层（V1）的大脑激活。在最初几周的训练中，与训练视野象限相对应的V1区域的大脑活动和任务表现都有所增加。然而，当表现水平达到饱和并保持在恒定水平时，相应区域的大脑活动下降到训练前的水平。这些结果表明，在知觉学习的时间过程中存在不同的时间阶段，这与视觉皮层BOLD活动的差异动力学有关。
Perceptual learning is regarded as a manifestation of experience-dependent plasticity in the sensory systems, yet the underlying neural mechanisms remain unclear. We measured the dynamics of performance on a visual task and brain activation in the human primary visual cortex (V1) across the time course of perceptual learning. Within the first few weeks of training, brain activation in a V1 subregion corresponding to the trained visual field quadrant and task performance both increased. However, while performance levels then saturated and were maintained at a constant level, brain activation in the corresponding areas decreased to the level observed before training. These findings indicate that there are distinct temporal phases in the time course of perceptual learning, related to differential dynamics of BOLD activity in visual cortex.