The International HIV Dementia Scale Is a Useful Screening Tool for HIV-Associated Dementia/Cognitive Impairment in HIV-Infected Adults in Yaounde-Cameroon
The International HIV Dementia Scale Is a Useful Screening Tool for HIV-Associated Dementia/Cognitive Impairment in HIV-Infected Adults in Yaounde-Cameroon
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DOI：
10.1097/qai.0b013e318183a9df
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发表时间：
2008-12-01
影响因子：
3.6
通讯作者：
Muna, Walinjom F.
中科院分区：
文献类型：
--
作者：
Njamnshi, Alfred K.;Djientcheu, Vincent de Paul;Muna, Walinjom F.
目的：作为 HIV 相关痴呆 (HAD) 系列研究的基线。我们试图评估最近开发的国际艾滋病毒痴呆量表（IHDS）作为雅温得-喀麦隆艾滋病毒阳性成人的 HAD 或 HIV 相关认知障碍（HACI）筛查工具的有用性。 设计：在资源丰富的国家，HAD/HACI 的发生率在很大程度上是未知的。在喀麦隆，很少有研究表明 HAD 可能很常见，但迄今为止，有专门的研究调查了这个问题。因此，我们采用病例对照研究设计，将 HIV 阳性成人作为病例，将 HIV 阴性个体作为对照，以确定 IHDS 作为筛查工具的有用性。方法：在所有 HIV 门诊接受 LIP 的 HIV 阳性成人与 HIV 阴性受试者进行年龄和性别匹配，并使用 IHDS 进行筛查。结果：总体。对 204 名 HIV 阳性个体和 204 名 HIV 阴性受试者进行了筛查。 HIV 阳性受试者的 IHDS 平均总分为 10.87，显着低于 HIV 阴性受试者的 IHDS 平均总分 11.28（P = 0.00）。异常分数（
Objective: As a baseline for it series of studies on HIV-associated dementia (HAD). we sought to assess the usefulness of the recently developed International HIV Dementia Scale (IHDS) as a screening tool for HAD or HIV-associated cognitive impairment (HACI) in HIV-positive adults in Yaounde-Cameroon.Design: The frequency of HAD/HACI is largely unknown in resource-linuted countries. In Cameroon, few studies suggest that HAD may be frequent but tic) specific study had so far investigated the problem. We therefore used a case-control study design involving HIV-positive adults as cases and HIV-negative individuals as controls to determine the usefulness of the IHDS as a screening instrument.Methods: HIV-positive adults followed LIP in all HIV outpatient clinic were matched to HIV negative subjects for age and sex and screened using IHDS.Results: Overall. 204 HIV-positive individuals and 204 HIV-negative subjects were screened. The HIV-positive subjects had a significantly lower IHDS mean total score of 10.87 compared with the HIV negative subjects with a score of 11.28 (P = 0.00). Abnormal scores (