Role of Chloride Formed on Anodized Titanium Surfaces Against an Oral Microorganism
Role of Chloride Formed on Anodized Titanium Surfaces Against an Oral Microorganism
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DOI：
10.1177/0885328209349316
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发表时间：
2010-08-01
影响因子：
2.9
通讯作者：
Igarashi, Takeshi
中科院分区：
文献类型：
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作者：
Deng, Jia-Yin;Arimoto, Takafumi;Igarashi, Takeshi
在电解液中放电后进行阳极化处理的改性钛表面提供了对口腔细菌的抗菌活性以及骨传导性。然而，这种对口腔细菌的抗菌作用的机制仍然不清楚。本研究的目的是探讨是否是氯化物或亲水性的阳极氧化钛，这是有效的对口腔细菌。钛板在含或不含氯化物的各种电解液中进行阳极氧化，并进行表征。然后评估每个标本上变形链球菌的存活率。结果表明，在各种氯化物溶液中，钛表面阳极氧化生成的TiCl3产生的HClO的过氧化作用有效地杀死了粘附的S。在表面上存在的亲水性不显示出抗菌活性，而仅存在亲水性不显示出抗菌活性。这种在氯化物溶液中对钛表面进行阳极氧化的方法可以为骨科或牙科植入物系统提供一种新的策略。
A modified titanium surface, anodized after being discharged in electrolytes, provides antibacterial activity against oral bacteria as well as osteoconductivity. However, the mechanism of this antibacterial effect against oral bacteria is still unclear. This study aims to investigate whether it is the chloride or the hydrophilicity properties of the anodized titanium, which is effective against the oral bacteria. Titanium plates are anodized in various electrolytes with or without chloride and are characterized. Then the survival of Streptococcus mutans on each specimen is evaluated. The results demonstrate that the peroxidation effects of HClO generated from the TiCl3 formed on the titanium surface anodized in various chloride solutions efficiently killed adherent S. mutans on the surface whereas the presence of hydrophilicity alone do not demonstrate antibacterial activity. This method of anodizing titanium surface in a chloride solution may provide a novel strategy for use in orthopedic or dental implant systems.