Serum vitamin D insufficiency and diabetes status in three ethnic minority groups.
Serum vitamin D insufficiency and diabetes status in three ethnic minority groups.
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三个少数民族的血清维生素 D 不足和糖尿病状况。
DOI：
10.1007/s10903-012-9634-2
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发表时间：
2012
影响因子：
1.9
通讯作者：
Huffman,FatmaG
中科院分区：
文献类型：
--
作者：
Shaban,LamyaH;Zarini,GustavoG;Exebio,JoelC;Sukhram,ShirynD;Huffman,FatmaG
本研究的目的是调查三个种族中 25-羟基维生素 D [25(OH)D] 水平与糖尿病状况之间的关联。这项横断面研究包括来自美国佛罗里达州的患有或不患有 2 型糖尿病 (T2D) 的古巴裔美国人 (n= 199)、海地裔美国人 (n= 253) 和非裔美国人 (n= 248)。参与者的招募是通过邮件列表（古巴裔美国人和非裔美国人）和社区来源（海地裔美国人）进行的。调整后的逻辑回归分析表明，不同种族 [P<0.001]、糖尿病状况 [P<0.001] 及其相互作用 [P<0.001] 25(OH)D 水平不足的几率存在显着差异。 Holm 的改良 Bonferroni 方法显示，与所有其他群体相比，只有没有 T2D 的古巴裔美国人 25(OH)D 不足的几率显着较低。海地裔美国人和非裔美国人参与者以及患有 T2D 的参与者 25(OH)D 不足的风险最大。未来的研究应重点关注维生素 D 补充剂和跨种族糖尿病结局的作用。
The purpose of this study was to investigate the association between 25-hydroxyvitamin D [25(OH)D] levels and diabetes status in three ethnicities. This cross sectional study included Cuban Americans (n= 199), Haitian Americans (n= 253) and African Americans (n= 248) with and without type 2 diabetes (T2D) from Florida, U.S. Recruitment of participants was through mailing lists (Cuban Americans and African Americans) and community based sources (Haitian Americans). Adjusted logistic regression analysis indicated significant differences in the odds of having insufficient 25(OH)D levels by ethnicity [P< 0.001], diabetes status [P< 0.001], and their interaction [P< 0.001]. Holm’s modified Bonferroni method showed that only Cuban Americans without T2D had significantly lower odds of having insufficient 25(OH)D compared to all other groups. Haitian American and African American participants and participants having T2D had the greatest risk of 25(OH)D insufficiency. Future studies should focus on the role of vitamin D supplementation and diabetes outcomes across ethnic groups.