Intelligent gels-artificial soft tissue for the next era
Intelligent gels-artificial soft tissue for the next era
复制标题
智能凝胶——下一代人造软组织
DOI：
10.1002/pi.6305
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发表时间：
2021
影响因子：
3.2
通讯作者：
Yoshihito Osada
中科院分区：
文献类型：
--
作者：
Ken-Ichi Sano;Ryuzo Kawamura;Yoshihito Osada
人体的大部分是由软组织组成的，软组织是一种水凝胶，主要由胶原和蛋白多糖纤维网络组成。在过去的几十年里，人们已经做出了很大的努力来利用合成和生物水凝胶来创造人造组织。例如，优质水凝胶表现出极佳的机械性能，如结缔组织，极低的摩擦系数，如滑膜软骨。使用纳米点水凝胶显示各种结构颜色的可调光子晶体是另一个独特的例子。还开发了具有肌肉样运动的各种类型的凝胶致动器。本文在简要介绍细胞外基质的基础上，介绍了具有组织类功能的智能凝胶的最新发展趋势和研究成果。©2021工业化学学会。
A substantial part of the human body is made of soft tissue which is a hydrogel consisting mainly of collagen and proteoglycan fiber networks. In the last decades, great effort has been made to create artificial tissues using synthetic and biological hydrogels. Examples are superior hydrogels which exhibit excellent mechanical properties like connective tissue and extremely low frictional coefficients like synovial cartilage. A tunable photonic crystal showing a variety of structural colors using nano‐dotted hydrogel is another unique example. Various types of gel actuators with muscle‐like motility have also been developed. In this article recent trends and achievements of intelligent gels with tissue‐like functions are described after a brief overview of the extracellular matrix. © 2021 Society of Industrial Chemistry.