Plasticity of cortical hand muscle representation in patients with hemifacial spasm
Plasticity of cortical hand muscle representation in patients with hemifacial spasm
复制标题
DOI：
10.1016/s0304-3940(99)00574-1
复制
发表时间：
1999-09-03
影响因子：
2.5
通讯作者：
Malin, JP
中科院分区：
文献类型：
--
作者：
Liepert, J;Oreja-Guevara, C;Malin, JP
为了研究人类运动皮质中面部和手部表征之间的相互作用，我们研究了肉毒杆菌毒素治疗前后面肌痉挛的患者。采用经颅磁刺激技术检测双侧拇短展肌(APB)皮质运动输出图。治疗前，猿猴面部肌肉收缩(IAPB)同侧的面积明显小于对侧，治疗成功2周后，IAPB的输出区明显扩大，并向面部的方向扩张。结果表明，成人运动皮质中手和脸表征之间的相互作用依赖于活动。(C)1999爱思唯尔爱尔兰科学有限公司。保留所有权利。
To investigate interactions between face and hand representations in the human motor cortex, we studied patients with a hemifacial spasm before and after treatment with Botulinum toxin. Focal transcranial magnetic stimulation was used to assess the cortical motor output map of the abductor pollicis brevis muscle (APB) on both sides. Prior to therapy the representation of the APE ipsilateral to the facial muscle contractions (iAPB) was significantly smaller than on the contralateral side, Two weeks after successful therapy, the iAPB output area was significantly enlarged and expanded into the direction of the face representation. The results indicate activity dependent interactions between hand and face representations in the adult human motor cortex. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.