The technology behind glucose meters: Test strips
The technology behind glucose meters: Test strips
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DOI：
10.1089/dia.2008.0005
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发表时间：
2008-01-01
影响因子：
5.4
通讯作者：
Surridge, Nigel
中科院分区：
文献类型：
--
作者：
Hoenes, Joachim;Mueller, Peter;Surridge, Nigel
血糖仪是糖尿病患者接近正常生活，避免急性和晚期并发症的基础。血糖仪背后的主要技术部分是由试纸组成的。本文试图对试纸的原理进行概述和一些见解。它们以干层的形式含有酶、辅酶、介质和指示剂，并将血糖浓度转换成仪表可读的信号。测试条的化学性质和设计决定了测试的速度、特异性、准确度和精密度。在过去的几十年里，他们已经发展到在5秒内完成这项工作，用不到1毫升的血液。我们坚信，它们将得到进一步发展，并在未来几十年保持重要地位。
Blood glucose meters are the basis for people with diabetes to live a near-normal life avoiding acute and late complications. The main part of the technology behind blood glucose meters is formed by test strips. This paper tries to give an overview and some insight into the principles of test strips. They contain enzymes, coenzymes, mediators, and indicators in the form of a dry layer and convert blood glucose concentration into a signal that is readable by the meter. Measurement speed, specificity, accuracy, and precision are dominated by test strip chemistry and design. During the last decades, they have been developed to do the job in 5 s, with less than 1 mu L of blood. It is our firm belief that they will be developed further and stay important for decades to come.