Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder

Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder
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DOI:
10.1038/mp.2011.8
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发表时间:
2012-04-01
影响因子:
11
通讯作者:
Muehleisen, T. W.
Muehleisen, T. W.
中科院分区:
医学1区
文献类型:
--
作者:
Priebe, L.;Degenhardt, F. A.;Muehleisen, T. W.

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我们使用全基因组单核苷酸多态(SNP)数据在882例双相情感障碍(BD)患者和872名基于人群的对照中搜索拷贝数变异(CNV)的存在。共有291名患者(33%)有早期发病年龄。
We used genome-wide single nucleotide polymorphism (SNP) data to search for the presence of copy number variants (CNVs) in 882 patients with bipolar disorder (BD) and 872 population-based controls. A total of 291 (33%) patients had an early age-at-onset