Bias-contingent attention bias modification and attention control training in treatment of PTSD: a randomized control trial.
Bias-contingent attention bias modification and attention control training in treatment of PTSD: a randomized control trial.
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DOI：
10.1017/s0033291718003367
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发表时间：
2019-10
影响因子：
6.9
通讯作者：
Neria Y
中科院分区：
文献类型：
--
作者：
Lazarov A;Suarez-Jimenez B;Abend R;Naim R;Shvil E;Helpman L;Zhu X;Papini S;Duroski A;Rom R;Schneier FR;Pine DS;Bar-Haim Y;Neria Y
比较注意力控制训练（ACT）和注意力偏差修正（ABM）治疗创伤后应激障碍（PTSD）的随机对照试验（RCT）显示出不同的结果。目前的随机对照试验通过比较 ACT 和一种新型偏倚相关 ABM (BC-ABM) 的功效，扩展了现有文献，其中训练方向取决于治疗前注意力偏向 (AB) 的方向，在患有 PTSD 的平民患者样本中。 50 名寻求治疗的 PTSD 平民患者被随机分配到 ACT 组或 BC-ABM 组。在治疗前和治疗后获得临床医生和自我报告的 PTSD 和抑郁症测量值，以及 AB 和注意偏差变异性 (ABV)。与 BC-ABM 相比，在临床医生评价和自我报告的测量中，ACT 都能更大程度地减少 PTSD 和抑郁症状。 BC-ABM 条件成功地将 AB 转向预期的训练方向。在 ACT 组中，治疗前后 ABV 或 AB 没有显着变化。目前的 RCT 扩展了之前的结果，成为第一个应用 ABM（取决于预处理时的 AB）。这种个性化 BC-ABM 方法可显着减轻症状。然而，ACT 的减少幅度甚至更大，因此成为治疗 PTSD 的一种有前途的治疗方法。
Randomized control trials (RCTs) comparing attention control training (ACT) and attention bias modification (ABM) in posttraumatic stress disorder (PTSD) have shown mixed results. The current RCT extends the extant literature by comparing the efficacy of ACT and a novel bias-contingent-ABM (BC-ABM), in which direction of training is contingent upon the direction of pre-treatment attention bias (AB), in a sample of civilian patients with PTSD. Fifty treatment-seeking civilian patients with PTSD were randomly assigned to either ACT or BC-ABM. Clinician and self-report measures of PTSD and depression, as well as AB and attention bias variability (ABV), were acquired pre- and post-treatment. ACT yielded greater reductions in PTSD and depressive symptoms on both clinician-rated and self-reported measures compared with BC-ABM. The BC-ABM condition successfully shifted ABs in the intended training direction. In the ACT group, there was no significant change in ABV or AB from pre- to post-treatment. The current RCT extends previous results in being the first to apply ABM that is contingent upon AB at pre-treatment. This personalized BC-ABM approach is associated with significant reductions in symptoms. However, ACT produces even greater reductions, thereby emerging as a promising treatment for PTSD.