Survival of extremely premature babies in a geographically defined population: prospective cohort study of 1994-9 compared with 2000-5

Survival of extremely premature babies in a geographically defined population: prospective cohort study of 1994-9 compared with 2000-5
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DOI:
10.1136/bmj.39555.670718.be
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发表时间:
2008-05-31
影响因子:
105.7
通讯作者:
Draper, Elizabeth S.
Draper, Elizabeth S.
中科院分区:
医学1区
文献类型:
--
作者:
Field, David J.;Dorling, Jon S.;Draper, Elizabeth S.

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目的评估26周前出生的婴儿存活率的变化。设计前瞻性队列研究,在地理上定义的population.Setting前特伦特健康地区的英国。主题所有出生在22 + 0至25+6周的母亲怀孕生活在该地区的婴儿。终止被排除,但所有其他出生的婴儿活着在一套tabour或交付过程中包括。主要结果措施的结果为所有婴儿被归类为死产,死亡没有入院新生儿重症监护,死亡前出院新生儿重症监护,并存活出院回家在两个时间段:结果1994-9年和2000-5年两个时期婴儿在产房死亡的比例相似,但存活出院的婴儿人数明显增加(P
Objective To assess changes in survival for infants born before 26 completed weeks of gestation.Design Prospective cohort study in a geographically defined population.Setting Former Trent health region of the United Kingdom.Subjects All infants born at 22 + 0 to 25+6 weeks' gestation to mothers living in the region. Terminations were excluded but all other births of babies alive at the on set of tabour or the delivery process were included.Main outcome measures Outcome for all infants was categorised as stillbirth, death without admission to neonatal intensive care, death before discharge from neonatal intensive care, and survival to discharge home in two time periods: 1994-9 and 2000-5 inclusive.Results The proportion of infants dying in delivery rooms was similar in the two periods, but a significant improvement was seen in the number of infants surviving to discharge (P