The structural and functional diversification of the Toxicofera reptile venom system
The structural and functional diversification of the Toxicofera reptile venom system
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DOI：
10.1016/j.toxicon.2012.02.013
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发表时间：
2012-09-15
期刊：
影响因子：
2.8
通讯作者：
Jackson, Timothy N. W.
中科院分区：
文献类型：
--
作者：
Fry, Bryan G.;Casewell, Nicholas R.;Jackson, Timothy N. W.
描述了爬行动物毒液系统的进化起源和多样化。高阶分子系统发育的分辨率已经清楚地确定了毒液系统是蛇的祖先。讨论了蜥蜴毒液系统的多样化，以及这些分类群（特别是科莫多蜥蜴）的毒液传递在行为生态学中的作用。总结了蛇的毒液系统的更广泛的多样化，包括它在一些分支中的损失。最后，我们讨论了有争议的“毒液”定义问题，支持承认毒液传递系统和毒素本身同源性的进化定义。(c) 2012 Elsevier Ltd.版权所有。
The evolutionary origin and diversification of the reptilian venom system is described. The resolution of higher-order molecular phylogenetics has clearly established that a venom system is ancestral to snakes. The diversification of the venom system within lizards is discussed, as is the role of venom delivery in the behavioural ecology of these taxa (particularly Varanus komodoensis). The more extensive diversification of the venom system in snakes is summarised, including its loss in some clades. Finally, we discuss the contentious issue of a definition for "venom", supporting an evolutionary definition that recognises the homology of both the venom delivery systems and the toxins themselves. (c) 2012 Elsevier Ltd. All rights reserved.