Partnering to Harmonize IRBs for Community-Engaged Research to Reduce Health Disparities
Partnering to Harmonize IRBs for Community-Engaged Research to Reduce Health Disparities
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DOI：
10.1353/hpu.2011.0157
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发表时间：
2011-11-01
影响因子：
1.4
通讯作者：
Norris, Keith C.
中科院分区：
文献类型：
--
作者：
Hammatt, Zoe H.;Nishitani, Junko;Norris, Keith C.
健康差异研究的新进展包括经常在多个社区和学术场所进行的对照试验和比较有效性研究。不同机构审查委员会的审查是及时和有效开展此类研究的主要障碍。当研究涉及少数民族和服务不足的社区以及多个地理区域时，机构要求和对道德标准的解释可能会有很大差异。这种变化可能会使知情同意过程和研究方案复杂化，并可能损害受试者的尊重和试验质量。此外，多次IRB审查可能导致不必要的延误，危及执行合作项目的资金和能力。针对这些问题，少数民族机构研究中心（RCMI）转化研究网络（RTRN）正在开发一种社区合作的方法，以简化IRB审查其18个RCMI受资助机构的联盟，这将确保合规性，同时提高健康差异研究的质量。
Emerging advances in health disparities research include controlled trials and comparative effectiveness studies that are frequently conducted at multiple community and academic sites. Review by different institutional review boards (IRBs) presents a major impediment to the timely and effective conduct of such research. When research involves minority and underserved communities as well as multiple geographic regions, institutional requirements and interpretation of ethical standards may vary substantially. Such variations can complicate the informed consent process and research protocol, and may undermine participant respect and trial quality. In addition, multiple IRB review can lead to unnecessary delays, jeopardizing funding and capacity to perform collaborative projects. In response to these issues, the Research Centers in Minority Institutions (RCMI) Translational Research Network (RTRN) is developing a community-partnered approach to streamlining IRB review across its consortium of 18 RCMI grantee institutions that will ensure compliance while enhancing the quality of health disparities research.