Global cardiac function using fast breath-hold MRI: Validation of new acquisition and analysis techniques

Global cardiac function using fast breath-hold MRI: Validation of new acquisition and analysis techniques
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DOI:
10.1002/mrm.1910370510
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发表时间:
1997-05-01
影响因子:
3.3
通讯作者:
Axel, L
Axel, L
中科院分区:
医学3区
文献类型:
--
作者:
Bloomgarden, DC;Fayad, ZA;Axel, L

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全球心功能参数的计算已经使用快速、分段的k空间、屏气、梯度回波、磁共振图像进行了验证。使用1.5T临床扫描仪采集模体、实验动物、正常志愿者和患者的图像,使用两个相控阵表面线圈以多线圈模式对人体进行成像,使用基于活动轮廓模型方法的新的交互式半自动方法提取心肌轮廓,在短轴方向获取图像,并使用新的成像和分析策略在旋转平面的长轴方向上提供更好的瓣膜平面和心尖部的清晰度,并且还减少了采样整个心脏所需的切片数量(与短轴方法相比),通过计算模体的体积和动物心脏的左、右室质量来完成验证。将正常志愿者和患者的MRI功能参数分别与超声心动图和放射性核素血管造影的功能参数进行比较。
Calculation of global cardiac function parameters has been validated using fast, segmented k-space, breath-hold, gradient-echo, magnetic resonance images. Images of phantoms, experimental animals, normal volunteers, and patients were acquired with a 1.5 T clinical scanner, Humans were imaged using two phased-array surface coils in multicoil mode, Myocardial contours were extracted using a new interactive, semi-automated method based on the active contour model method, Images were acquired in the short-axis orientation, and, using a new imaging and analysis strategy, in rotating plane long-axis orientations, to provide better definition of the valve planes and the apex, and also to reduce the number of slices (compared with the short-axis method) required to sample the whole heart, Validation was accomplished through calculation of the volumes of phantoms and left and right ventricular masses of animal hearts. Functional parameters from MRI were compared with those from echocardiograms and radionuclide angiograms in normal volunteers and patients, respectively.