Locomotive Syndrome is associated with chronic pain and poor quality of life in Brazilian oldest old: LOCOMOV Project
Locomotive Syndrome is associated with chronic pain and poor quality of life in Brazilian oldest old: LOCOMOV Project
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DOI：
10.1016/j.jos.2020.02.007
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发表时间：
2021-02-18
影响因子：
1.7
通讯作者：
Santos, Fania Cristina
中科院分区：
文献类型：
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作者：
Fonseca Batista Arbex, Maria Carolyna;Frazao Okazaki, Jane Erika;Santos, Fania Cristina
背景资料：2007年，日本骨科协会（Japanese Orthopedic Association）将运动器官功能障碍与潜在的独立性丧失的概念定义为“机车综合征”（Locomotive Syndrome，LS）。本研究的目的是确定LS的特征，并为巴西人群建立老年运动功能量表（GLFS 25-p）的诊断临界值。方法：对LOCOMOV项目年龄>= 80岁的独立门诊患者队列进行了一项横断面观察研究。应用基本和工具性日常生活活动（分别为Katz和Lawton）和生活质量（WHOQOL-Bref）的功能状态量表，以及老年运动功能量表（GLFS 25-p）来识别LS患者。采用5次坐立试验、4 m步行速度、两步试验、单腿睁眼站立时间和握力试验评估活动度。使用Student t检验、卡方检验和多元logistic回归（逐步）分析数据。显著性水平设定为0.05（5%）。结果：评估了102名平均年龄为87.3（+/- 4.2）岁且主要为女性（73.5%）的个体样本。根据GLFS 25-p评估，我们确定LS诊断的临界值为19（敏感性为0.86，特异性为0.67），在样本中发现该综合征的高患病率（55%）。在多元回归分析中，LS与慢性疼痛直接相关（OR 22.24，95%CI 3.13-157.87），使用步行装置（OR 17.121，95%CI 1.94-150.49），与步态速度≥ 0.8 m/s呈负相关（OR 0.42，95%CI 0.006-0.278），健康状况良好（OR 0.153，95%CI 0.029-0.799）和男性（OR 0.086，95%CI 0.0105-0.714）。在这项调查中，年龄最大的老年人的LS被证明是一种非常常见的疾病，尤其是在女性中，并且与慢性疼痛密切相关，身体测试表现较差，生活质量较差。(C)2020年日本骨科协会。Elsevier B. V.出版，保留所有权利。
Background: In 2007, the Japanese Orthopedic Association established the term "Locomotive Syndrome" (LS) for the concept of locomotor organ dysfunction with potential loss of independence. The purpose of this study was to identify characteristics of LS and establish a diagnostic cut-off for the Geriatric Locomotive Function Scale (GLFS 25-p) for the Brazilian population.Methods: A cross-sectional observational study of the LOCOMOV Project cohort of independent outpatients aged >= 80 years was conducted. Questionnaires on functional status in Basic and Instrumental Activities of Daily Living (Katz and Lawton, respectively) and quality of life (WHOQOL-Bref) were applied, together with the Geriatric Locomotive Function Scale (GLFS 25-p) to identify individuals with LS. Mobility was assessed using the five-times sit-to-stand test, 4-m gait speed, two-step test, one-leg standing time with eyes open and hand-grip test. The data were analyzed using Student's t-test, the Chi-Square test, and multiple logistic regression (stepwise). The significance level was set at 0.05 (5%).Results: A sample of 102 individuals with mean age of 87.3 (+/- 4.2) years and predominantly female (73.5%) was assessed. We determined a cut-off score of 19 (sensitivity of 0.86 and specificity of 0.67) for diagnosis of LS, as assessed by the GLFS 25-p, and a high prevalence (55%) of the syndrome was found in the sample. In the multiple regression analysis, LS was directly associated with chronic pain (OR 22.24, 95%CI 3.13-157.87), use of a walking device (OR 17.121, 95%CI 1.94-150.49), and inversely associated with gait speed >= 0.8 m/s (OR 0.42, 95%CI 0.006-0.278), perception of good health (OR 0.153, 95%CI 0.029-0.799) and male gender (OR 0.086, 95%CI 0.0105-0.714).Conclusion: The LS in the oldest old proved a very common condition in this survey, especially in women, and was strongly associated with chronic pain, worse performance on physical tests and poor quality of life. (C) 2020 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.