Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review
Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review
复制标题
DOI：
10.1371/journal.pone.0140290
复制
发表时间：
2015-10-09
期刊：
影响因子：
3.7
通讯作者：
Moher, David
中科院分区：
文献类型：
--
作者：
Hersi, Mona;Stevens, Adrienne;Moher, David
背景在一项协议的指导下，进行了一项快速审查，以便为世界卫生组织在西非丝状病毒病持续爆发（2013年至今）的背景下制定个人防护装备指南提供信息，重点是直接护理埃博拉或马尔堡病毒病患者的医护人员。方法检索了电子数据库和灰色文献来源。资格标准最初包括以英语或法语报告的埃博拉病毒和马尔堡病毒病的比较研究，但由于研究缺乏，标准扩展到其他病毒性出血热和非比较设计的研究。经过标题和摘要筛选（排除两人）后，对潜在相关文章的全文报告进行一式两份的评估。百分之五十七的提取信息得到验证。建议评估、制定和评估框架的分级用于告知证据评估的质量。结果找到了 30 项非比较性研究（8 项与埃博拉病毒病相关），其中 27 项提供了病毒传播的数据。个人防护装备成分和感染预防和控制方案的报告普遍较差。结论没有足够的证据来得出有关各种类型个人防护装备的比较有效性的结论。迫切需要进行更多研究来确定照顾丝状病毒患者的医护人员的最佳个人防护装备。
BackgroundA rapid review, guided by a protocol, was conducted to inform development of the World Health Organization's guideline on personal protective equipment in the context of the ongoing (2013-present) Western African filovirus disease outbreak, with a focus on health care workers directly caring for patients with Ebola or Marburg virus diseases.MethodsElectronic databases and grey literature sources were searched. Eligibility criteria initially included comparative studies on Ebola and Marburg virus diseases reported in English or French, but criteria were expanded to studies on other viral hemorrhagic fevers and non-comparative designs due to the paucity of studies. After title and abstract screening (two people to exclude), full-text reports of potentially relevant articles were assessed in duplicate. Fifty-seven percent of extraction information was verified. The Grading of Recommendations Assessment, Development and Evaluation framework was used to inform the quality of evidence assessments.ResultsThirty non-comparative studies (8 related to Ebola virus disease) were located, and 27 provided data on viral transmission. Reporting of personal protective equipment components and infection prevention and control protocols was generally poor.ConclusionsInsufficient evidence exists to draw conclusions regarding the comparative effectiveness of various types of personal protective equipment. Additional research is urgently needed to determine optimal PPE for health care workers caring for patients with filovirus.