Role of fNIRS technology in observing the effect of needling Hegu (LI 4) on the functions of prefrontal cortex in healthy volunteers
Role of fNIRS technology in observing the effect of needling Hegu (LI 4) on the functions of prefrontal cortex in healthy volunteers
复制标题
fNIRS技术在观察针刺合谷（LI 4）对健康志愿者前额皮质功能影响中的作用
DOI：
10.1007/s11726-017-0982-2
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发表时间：
2017-04-01
影响因子：
0.5
通讯作者：
Yan Xing-ke
中科院分区：
文献类型：
--
作者：
Han Ya-di;Yuan Bo;Yan Xing-ke
ObjectiveTo observe the effect of needling Hegu (LI 4) on functions of the prefrontal cortex using the functional near infrared spectroscopy (fNIRS).MethodsA total of 12 healthy volunteers were randomly assigned to an acupuncture group (n=6) and a control group (n=6). The control group received no intervention. The acupuncture group received needling Hegu (LI 4) on the right side. The real-time concentration changes of oxygenated hemoglobin (HbO2), deoxygenated hemoglobin (d-Hb) and total hemoglobin (t-Hb) in the prefrontal cortex were recorded using the fNIRS, allowing for effect analysis of needling Hegu (LI 4) on the functions of the prefrontal cortex.ResultsCompared with the control group, the HbO2 and t-Hb concentrations were increased in the acupuncture group and there were between-group statistical significances (both P<0.05). There was no between-group statistical significance in d-Hb concentration (P>0.05).Conclusion摘要目的利用功能近红外光谱成像(fNIRS)技术观察针刺合谷穴对健康人前额叶皮层功能的影响。方法将12 名健康受试者根据随机数字表随机分为对照组和针刺组, 每组6 例。对照组不予任何干预, 针刺组予以针刺右 侧合谷穴。利用近红外脑功能成像仪实时记录前额叶皮层区含氧血红蛋白(HbO2)、脱氧血红蛋白(d-Hb)和总血红 蛋白(t-Hb)的浓度变化, 分析针刺合谷穴对前额叶皮层功能的影响。结果与对照组比较, 针刺组HbO2 和t-Hb 浓度增高, 组间差异均有统计学意义(均P<0.05); 而d-Hb 浓度组间差异无统计学意义(P>0.05)。结论针刺合谷穴能引起前额叶皮层的广泛激活, 对前额叶皮层脑功能有明显的影响。