Radial artery grafts in women: Utilization and results
Radial artery grafts in women: Utilization and results
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DOI：
10.1016/j.athoracsur.2005.02.055
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发表时间：
2005-08-01
影响因子：
4.6
通讯作者：
Damiano, RJ
中科院分区：
文献类型：
--
作者：
Lawton, JS;Barner, HB;Damiano, RJ
背景尽管使用左乳内动脉有已知的生存益处，但与男性相比，女性使用左乳内动脉的频率较低。本研究评估了以下假设：女性桡动脉移植物的使用频率低于男性，女性桡动脉比男性小，以及桡动脉的使用影响女性的手术死亡率和长期生存率。在2，633例接受隔离冠状动脉搭桥术的患者中评价了桡动脉移植物的使用。比较了207例术中测量桡动脉直径和流量的患者的桡动脉大小和流量。倾向评分被用来比较短期和长期的结果在匹配队列的588名妇女。在862名接受了单独冠状动脉旁路移植术的女性（33%）中，只有301名（35%）接受了桡动脉移植术，而男性的比例为44%（786/1771，p < 0.001）。女性桡动脉的大小和流量明显较少。手术死亡率在桡动脉移植组和未移植组之间无差异;然而，5年生存率在桡动脉移植组明显优于未移植组。女性接受桡动脉移植比男性少。女性桡动脉的大小和流量明显小于男性。桡动脉移植物的使用并不影响女性的手术死亡率。然而，接受桡动脉移植的女性的5年生存率明显优于未接受桡动脉移植的女性。
Background. Despite a known survival benefit with the use of the left internal mammary artery, it is used less frequently in women when compared with men. This study evaluated the hypotheses that the radial artery graft is used less frequently in women compared with men, that the radial artery is smaller in women compared with men, and that the use of the radial artery influences operative mortality and long-term survival in women.Methods. The use of a radial artery graft was evaluated in 2,633 patients who underwent isolated coronary artery bypass. Radial artery size and flow were compared in 207 patients who had intraoperative radial artery diameter and flow measurements. Propensity scoring was utilized to compare short- and long-term outcomes in a matched cohort of 588 women.Results. Of 862 women (33%) who had isolated coronary artery bypass grafting, only 301 (35%) received a radial artery graft versus 44% of men (786 of 1,771, p < 0.001). Radial artery size and flow were significantly less in women. Operative mortality was not different between women with a radial artery graft and women without; however, 5-year survival was significantly better in women with a radial artery graft than in those without.Conclusions. Women received fewer radial artery grafts than men. Radial artery size and flow were significantly less in women than in men. Use of a radial artery graft did not influence operative mortality among women. However, 5-year survival among women who received a radial artery graft was significantly better than among women who did not.