High Yielding Microbubble Production Method.

High Yielding Microbubble Production Method.
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DOI:
10.1155/2016/3572827
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发表时间:
2016
影响因子:
--
通讯作者:
Pancholi K
Pancholi K
中科院分区:
生物学3区
文献类型:
--
作者:
Fiabane J;Prentice P;Pancholi K

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微流控方法产生微泡的缺点是产率低,易受(微)通道堵塞的影响。本文提出了一种在浓度超过30 × 106 mL−1时产生平均直径2.6 μm微泡的替代方法。在该方法中,当氮气-液体共流射流周围的空气高速通过100 μm孔时,液体射流内部流动的氮气被分解成微泡喷雾。所得微泡泡沫的多分散性指数为16%。此外,平均微泡直径与通道宽度之比小于0.025,大大减轻了生产过程中堵塞的发生。
Microfluidic approaches to microbubble production are generally disadvantaged by low yield and high susceptibility to (micro)channel blockages. This paper presents an alternative method of producing microbubbles of 2.6 μm mean diameter at concentrations in excess of 30 × 106 mL−1. In this method, the nitrogen gas flowing inside the liquid jet is disintegrated into spray of microbubble when air surrounding this coflowing nitrogen gas-liquid jet passes through a 100 μm orifice at high velocity. Resulting microbubble foam has the polydispersity index of 16%. Moreover, a ratio of mean microbubble diameter to channel width ratio was found to be less than 0.025, which substantially alleviates the occurrence of blockages during production.