Field evaluation of pyriproxyfen and spinosad mixture for the control of insecticide resistant Aedes aegypti in Martinique ( French West Indies)
Field evaluation of pyriproxyfen and spinosad mixture for the control of insecticide resistant Aedes aegypti in Martinique ( French West Indies)
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DOI：
10.1186/1756-3305-3-88
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发表时间：
2010-09-16
影响因子：
3.2
通讯作者：
Corbel, Vincent
中科院分区：
文献类型：
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作者：
Darriet, Frederic;Marcombe, Sebastien;Corbel, Vincent
背景：Ae的抗性。埃及人对杀虫剂的依赖已经很普遍，并在继续发展。它对热带国家旨在控制和预防登革热的方案来说是一个严重问题。针对这一问题，提出了防治Ae.埃及人正在研究如何最好地使用现有杀虫剂，特别是将具有不同作用方式的杀虫剂结合起来。结果如下：在这项研究中，我们评估了由吡丙醚（一种昆虫生长调节剂）和多杀菌素（一种生物农药）组成的混合物对Ae种群的操作效率。马提尼克岛的埃及伊蚊对拟除虫菊酯和有机磷杀虫剂有抗药性。第一步是评估吡丙醚和多杀菌素单独或联合使用时对Ae的效力。埃及伊蚊幼虫在模拟条件下。结果表明，吡丙醚+多杀菌素的混合物保持活性至少8个月，相比之下，单独的多杀菌素为3个月，而单独的吡丙醚为5个月。在第二步中，在经历自然条件的容器中，吡丙醚和多杀菌素分别将成虫羽化率保持在20%持续3周和3.5个月。按照相同的评价标准，吡丙醚+多杀菌素混合物保持有效4.5个月，表明具有不同作用模式的两种杀幼虫剂的组合起到增加处理的残余活性的作用。结论：吡丙醚和多杀菌素的混合物杀死幼虫和蛹，使其比任何一种杀虫剂的作用范围更广。这种混合物可以保留两种杀虫剂在公共卫生项目中的效用。
Background: The resistance of Ae. aegypti to insecticides is already widespread and continues to develop. It represents a serious problem for programmes aimed at the control and prevention of dengue in tropical countries. In the light of this problem measures to control Ae. aegypti are being orientated towards how best to use existing insecticides, notably by combining those that have different modes of action. Results: In this study we evaluated the operational efficiency of a mixture composed of pyriproxyfen (an insect growth regulator) and spinosad (a biopesticide) against a population of Ae. aegypti from Martinique resistant to pyrethroid and organophosphate insecticides. The first step consisted of evaluating the efficacy of pyriproxyfen and spinosad when used alone, or in combination, against Ae. aegypti larvae under simulated conditions. The results showed that the mixture of pyriproxyfen+spinosad remained active for at least 8 months, compared with 3 months for spinosad alone, and 5 months for pyriproxyfen alone. In a second step in containers experiencing natural conditions, pyriproxyfen and spinosad, maintained the rate of adult emergence at 20% for 3 weeks and 3.5 months, respectively. Following the same criteria of evaluation, the mixture pyriproxyfen+spinosad remained effective for 4.5 months, showing that the combination of the two larvicides with different modes of action acted to increase the residual activity of the treatment. Conclusion: The mixture of pyriproxyfen and spinosad kills larvae and pupae giving it a broader range of action than either insecticide. This mixture could preserve the utility of both insecticides in public health programs.