Zinc-rich afferents to the rat neocortex:: projections to the visual cortex traced with intracerebral selenite injections
Zinc-rich afferents to the rat neocortex:: projections to the visual cortex traced with intracerebral selenite injections
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DOI：
10.1016/s0891-0618(98)00035-0
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发表时间：
1998-08-01
影响因子：
2.8
通讯作者：
Bueno-López, JL
中科院分区：
文献类型：
--
作者：
Casanovas-Aguilar, C;Reblet, C;Bueno-López, JL
将亚硒酸钠注入大鼠枕叶皮质，用于富锌途径的特异性示踪。在同侧的视觉、眼眶和额叶皮质，以及对侧的同位和异位视觉区，发现了大量的标记胞体。在同侧的压后、顶叶、感觉运动、颞叶和嗅周皮质也发现了标记神经元。与皮质-皮质连接相反，除了屏状核中的少数标记神经元外，视觉皮质的上行传入并不富含锌。额外的注射显示了视觉皮层与眼眶和额叶皮层之间的相互富锌连接。后者的皮质也接受来自屏状核的上升的富锌传入。亚硒酸盐注射揭示了这些标记的神经元在新皮层的分层分布和形态。富锌神经元分布于第II-III、V和VI层。然而，在第IV层中没有发现。富锌胞体呈锥体和倒置神经元。皮层和皮层下视觉传入的化学性质的对比可能解释了这些系统之间的功能差异。(C)1998 Elsevier Science B. V.保留所有权利。
Infusion of sodium selenite to the occipital cortex of the rat was used for the specific tracing of zinc-rich pathways. Large numbers of labeled somata were found ipsilaterally in the visual, orbital and frontal cortices, and contralaterally in homotopic and heterotopic visual areas. Labeled neurons were also found ipsilaterally in the retrosplenial, parietal, sensory-motor, temporal and perirhinal cortex. In contrast to the cortico-cortical connections, ascending afferents to the visual cortex were not zinc-rich except for a few labeled neurons in the claustrum. Additional injections showed reciprocal zinc-rich connections between the visual cortex and the orbital and frontal cortices. The latter cortices also received ascending zinc-rich afferents from the claustrum. Selenite injections revealed the layered distribution and the morphology of these labeled neurons in the neocortex. Zinc-rich neurons were found in layers II-III, V and VI. However, none was found in layer IV. Zinc-rich somata appeared as pyramidal and inverted neurons. The contrasting chemical properties of cortical and subcortical visual afferents may account for the functional differences between these systems. (C) 1998 Elsevier Science B.V. All rights reserved.