Cognitive Impairment and Affective Disorders in Patients With Obstructive Sleep Apnea Syndrome
Cognitive Impairment and Affective Disorders in Patients With Obstructive Sleep Apnea Syndrome
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DOI：
10.3389/fpsyt.2018.00357
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发表时间：
2018-08-07
影响因子：
4.7
通讯作者：
Milanova, Vihra K.
中科院分区：
文献类型：
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作者：
Bilyukov, Radoslav G.;Nikolov, Martin S.;Milanova, Vihra K.
与睡眠有关的呼吸障碍可能伴随或由多种医疗条件引起。他们被认为是一个重大的医疗和社会问题。阻塞性睡眠呼吸暂停患者在白天嗜睡过多的同时，还会出现神经心理症状，如焦虑、注意力缺陷、认知障碍、抑郁症状等心理障碍，导致社会适应困难。被诊断为阻塞性睡眠呼吸暂停的患者表现出广泛的认知能力下降，包括记忆、注意力、精神运动速度、执行、语言和视觉空间技能。本研究的目的是调查阻塞性睡眠呼吸暂停综合征患者的认知功能和情感障碍，并与健康志愿者组成的对照组比较病例的频率和严重程度。我们的研究表明，睡眠呼吸暂停与认知障碍和情感变化之间存在联系。这种关系可以用综合征对患者的直接影响来解释，其中主要的联系因素是严重程度和白天过度嗜睡的分布。在治疗躯体疾病的同时，治疗病人的精神状态也非常重要。
Sleep-related breathing disorders could be accompanied by or caused by a variety of medical conditions. They are considered to be a significant medical and social problem. Together with excessive daytime sleepiness, patients with obstructive sleep apnea experience neuropsychological symptoms such as anxiety, attention deficits, cognitive impairment, depressive symptoms and other psychological disturbances leading to social adjustment difficulties. Patients diagnosed with obstructive sleep apnea demonstrate a decline in a wide spectrum of cognitive abilities, including memory, attention, psychomotor speed, executive, verbal and visual-spatial skills. The aim of this study is to investigate the cognitive functioning and affective disorders among patients with obstructive sleep apnea syndrome and to examine the frequency and severity of cases in comparison with a control group consisting of healthy volunteers. Our research has shown that there is a relation between sleep apnea and cognitive impairments and affective changes. This relation can be explained by the direct effect of the syndrome on the patient, where the main connecting factor is the severity and the distribution of excessive daytime sleepiness. Along with treatment of the somatic medical condition, it is extremely important that the patient's mental state is treated as well.