Alcaligenes faecalis Cellulitis After a Dog Bite Case Report and Literature Review

Alcaligenes faecalis Cellulitis After a Dog Bite Case Report and Literature Review
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DOI:
10.1097/pec.0000000000000645
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发表时间:
2017-07-01
影响因子:
1.4
通讯作者:
Harkness, Julia
Harkness, Julia
中科院分区:
医学4区
文献类型:
--
作者:
Chu, Andrew S.;Harkness, Julia

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粪碱性革兰氏菌是一种革兰氏阴性菌,常见于环境中,也可能是人类正常粪便菌群的一部分。虽然这种细菌的各种感染已经在儿科人群中被描述过,但以前还没有在狗咬伤后的感染中被确定为病原体。一例19个月大的男孩被犬咬伤后继发蜂窝织炎,口服抗生素治疗无效,并进展为发热和肿胀恶化。患者最终需要住院治疗,静脉注射抗生素,切开引流。伤口培养培养出粪芽孢杆菌,重组DNA序列分析证实了粪芽孢杆菌的身份。虽然在猫咬伤中发现了粪芽孢杆菌,但在狗咬伤后感染的文献中尚未引用粪芽孢杆菌。
Alcaligenes faecalis is a gram-negative organism that is commonly found in the environment and may also be a part of normal fecal flora in humans. Although various infections with this bacteria have been described in the pediatric population, it has not been previously identified in infections as the pathogen after a dog bite. A case of a 19-month-old boy is presented with a cellulitis secondary to a dog bite, which failed oral antibiotic therapy, and progressed to worsening fever and swelling. The patient ultimately required hospitalization, intravenous antibiotics, and incision and drainage. The wound culture grew A. faecalis, whose identity was confirmed through recombinant DNA sequence analysis. Although it has been identified in cat bite wounds, A. faecalis has not been cited in the literature before in an infection after a dog bite.