Phase-specific modulation of cortical motor output during movement observation
Phase-specific modulation of cortical motor output during movement observation
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DOI：
10.1097/00001756-200105250-00038
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发表时间：
2001-05-25
期刊：
影响因子：
1.7
通讯作者：
Pascual-Leone, A
中科院分区：
文献类型：
--
作者：
Gangitano, M;Mottaghy, FM;Pascual-Leone, A
采用经颅磁刺激（TMS）研究了运动的不同时相对皮层运动输出调制的影响。在被动观察过程中，显示了一个伸手抓握动作的视频剪辑，并提供了单个TMS脉冲。皮层刺激的时间与所示运动的阶段有关，将它们锁定在特定运动标志的出现上。经颅磁刺激在第一背侧骨间肌（FDI）诱发的运动诱发电位（MEP）的幅度受所观察到的手指开口的量的调制。这种效应的存在与运动前区的镜像神经元系统的概念是一致的，该镜像神经元系统还在时间编码方面耦合动作执行和动作观察。NeuroReport 12：1489-1492（C）2001 Lippincott威廉姆斯和威尔金斯。
The effects of different phases of an observed movement on the modulation of cortical motor output were studied by means of transcranial magnetic stimulation (TMS). A video-clip of a reaching-grasping action was shown and single TMS pulses were delivered during its passive observation. Times of cortical stimulation were related to the phases of the shown movement, locking them to the appearance of specific kinematic landmarks. The amplitude of the motor evoked potentials (MEPs) induced by TMS in the first dorsal interosseus (FDI) muscle was modulated by the amount of the observed finger aperture. The presence of such an effect is consistent with the notion of a mirror neuron system in premotor areas that couples action execution and action observation also in terms of temporal coding. NeuroReport 12:1489-1492 (C) 2001 Lippincott Williams & Wilkins.