The pharmacology and function of 5-HT3receptors

The pharmacology and function of 5-HT3receptors
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5-HT3受体的药理学和功能

DOI:
10.1016/0166-2236(86)90137-2
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发表时间:
1986
影响因子:
15.9
通讯作者:
G. Engel
G. Engel
中科院分区:
医学1区
文献类型:
--
作者:
B. Richardson;G. Engel

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After more than two decades of virtual stagnation, progress has recently been made in understanding the pharmacology and function of 5-hydroxytryptamine (5-HT) receptor subtypes. This has largely resulted from the use of new selective potent agonist and antagonist drugs that have now become generally available. Three basic subtypes of 5-HT receptors have been shown to exist — 5-HT1, 5-HT2and 5-HT3— and evidence is emerging to suggest heterogeneity within the 5-HT1and 5-HT3receptor categories. Here we review recent developments in this field with particular reference to the 5-HT3receptor, which is widely distributed throughout the peripheral nervous system where it mediates many of the excitatory actions of 5-HT.
兔主动脉中的 5-羟色胺受体:丁酰苯类似物的表征。
DOI: --
发表时间: 1984
期刊: The Journal of pharmacology and experimental therapeutics
影响因子: --
作者:
Maayani,S;Wilkinson,CW;Stollak,JS
通讯作者: Stollak,JS