Maternal Marital Status and Birth Outcomes: A Systematic Review and Meta-Analyses
Maternal Marital Status and Birth Outcomes: A Systematic Review and Meta-Analyses
复制标题
DOI：
10.1007/s10995-010-0654-z
复制
发表时间：
2011-10-01
影响因子：
2.3
通讯作者：
Ali, Samana
中科院分区：
文献类型：
--
作者：
Shah, Prakesh S.;Zao, Jamie;Ali, Samana
系统地审查已婚和未婚妇女中出生低出生体重（LBW）、早产（PTB）或小于胎龄儿（SGA）的婴儿的风险。检索Medline、Embase、CINAHL和已识别文章的参考书目，以查找英语研究。纳入了报告已婚和未婚（单身和同居）出生结局的研究。两名评审员独立收集数据，并评估研究质量，以确定样本选择、暴露评估、混杂因素、分析、结局评估和损耗方面的偏倚。采用随机效应模型对未校正和校正数据进行Meta分析，计算比值比（OR）和95%可信区间（CI）。纳入了21项低至中度偏倚风险的研究。与已婚母亲相比，（a）未婚母亲中LBW的未校正几率增加（OR 1.46，95%CI 1.25-1.71），单次（OR 1.65，95%CI 1.44-1.88）和同居（OR 1.29，95%CI 1.25-1.32）母亲;（B）未婚者PT B增高（OR 1.22，95%CI 1.14-1.31），单次（OR 1.54，95%CI 1.39-1.72）和同居（OR 1.15，95%CI 1.08-1.23）母亲和（c）SGA出生增加未婚（OR 1.45，95%CI 1.32-1.61）、单身母亲（OR 1.70，95%CI 1.47-1.97）和同居母亲（OR 1.36，95%CI 1.30-1.42）。调整后的比值估计值的荟萃分析证实了这些结果，比值略低。母亲未婚状态与LBW、PTB和SGA分娩的风险增加相关。
Systematically review risks of an infant being born with low birth weight (LBW), preterm birth (PTB) or small for gestational age (SGA) among married and unmarried women. Medline, Embase, CINAHL, and bibliographies of identified articles were searched for English language studies. Studies reporting birth outcomes of married and unmarried (single and cohabitant) were included. Two reviewers independently collected data and assessed the quality of the studies for biases in sample selection, exposure assessment, confounder, analytical, outcome assessments, and attrition. Meta-analyses were performed using random effect model for both unadjusted and adjusted data and odds ratio (OR), and 95% confidence interval (CI) were calculated. Twenty-one studies of low to moderate risk of bias were included. Compared to married mothers unadjusted odds of (a) LBW was increased among unmarried (OR 1.46, 95%CI 1.25-1.71), single (OR 1.65, 95%CI 1.44-1.88) and cohabitating (OR 1.29, 95%CI 1.25-1.32) mothers; (b) PTB was increased among unmarried (OR 1.22, 95%CI 1.14-1.31), single (OR 1.54, 95%CI 1.39-1.72) and cohabitating (OR 1.15, 95%CI 1.08-1.23) mothers and (c) SGA birth was increased among unmarried (OR 1.45, 95%CI 1.32-1.61), single (OR 1.70, 95%CI 1.47-1.97) and cohabitating (OR 1.36, 95%CI 1.30-1.42) mothers. Meta-analyses of adjusted odds estimates confirmed these findings at marginally lower odds. Maternal unmarried status is associated with an increased risk of LBW, PTB and SGA births.