Synthesis of the phthalide-containing anti-Helicobacter pylori agents CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108
Synthesis of the phthalide-containing anti-Helicobacter pylori agents CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108
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DOI：
10.1016/j.tet.2005.08.027
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发表时间：
2005-10-17
期刊：
影响因子：
2.1
通讯作者：
Sidford, M
中科院分区：
文献类型：
--
作者：
Brimble, MA;Flowers, CL;Sidford, M
用Wittig偶联的方法合成了抑制幽门螺杆菌的含酚类抗生素CJ-13,015、CJ-13,102、CJ-13,103、CJ-13,104和CJ-13,108。(C)2005爱思唯尔有限公司。保留所有权利。
Flexible racemic syntheses of the phthalide-containing antibiotics CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108 that inhibit Helicobacter pylori have been carried out in a convergent fashion by Wittig coupling of a phthalide-containing aldehyde fragment with an appropriate phosphorous ylide. (c) 2005 Elsevier Ltd. All rights reserved.