Strain‐Isolating Materials and Interfacial Physics for Soft Wearable Bioelectronics and Wireless, Motion Artifact‐Controlled Health Monitoring
Strain‐Isolating Materials and Interfacial Physics for Soft Wearable Bioelectronics and Wireless, Motion Artifact‐Controlled Health Monitoring
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DOI：
10.1002/adfm.202104070
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发表时间：
2021-06
影响因子：
19
通讯作者：
Nathan Rodeheaver;Robert Herbert;Yun-Soung Kim;Musa Mahmood;Hojoong Kim;Jae‐Woong Jeong;W. Yeo
中科院分区：
文献类型：
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作者：
Nathan Rodeheaver;Robert Herbert;Yun-Soung Kim;Musa Mahmood;Hojoong Kim;Jae‐Woong Jeong;W. Yeo
微传感器和柔性电子器件的最新发展允许通过将设备安装在胸部上来制造健康监测设备，包括用于住院监测和动态健康诊断的心电图（ECG）检测系统。尽管报告文章中的一些商业设备显示了便携式ECG记录的示例，但由于显著的运动伪影，它们丢失了有价值的数据。在这里，一类新的应变隔离材料，混合界面物理，和软材料封装的应变隔离，可穿戴软生物电子系统（SIS）的报告。传感器嵌入式应变隔离的基本机制是通过分析和计算研究相结合定义的，并通过动态实验进行验证。对软硬材料集成和隔离力学的全面研究提供了关键的设计特征，以最大限度地减少轻度和过度日常活动期间可能发生的运动伪影。无线、完全集成的SIS采用透气、穿孔膜，可以测量真实的实时、连续的生理数据，包括高质量的ECG、心率、呼吸率和活动。多个受试者的体内演示以及与商业设备的同步比较捕捉到了SIS的出色性能，提供了真实的世界，连续监测关键生理信号，在日常生活中连续8小时没有数据丢失，即使有夸张的身体运动。
Recent developments of micro‐sensors and flexible electronics allow for the manufacturing of health monitoring devices, including electrocardiogram (ECG) detection systems for inpatient monitoring and ambulatory health diagnosis, by mounting the device on the chest. Although some commercial devices in reported articles show examples of a portable recording of ECG, they lose valuable data due to significant motion artifacts. Here, a new class of strain‐isolating materials, hybrid interfacial physics, and soft material packaging for a strain‐isolated, wearable soft bioelectronic system (SIS) is reported. The fundamental mechanism of sensor‐embedded strain isolation is defined through a combination of analytical and computational studies and validated by dynamic experiments. Comprehensive research of hard‐soft material integration and isolation mechanics provides critical design features to minimize motion artifacts that can occur during both mild and excessive daily activities. A wireless, fully integrated SIS that incorporates a breathable, perforated membrane can measure real‐time, continuous physiological data, including high‐quality ECG, heart rate, respiratory rate, and activities. In vivo demonstration with multiple subjects and simultaneous comparison with commercial devices captures the SIS's outstanding performance, offering real‐world, continuous monitoring of the critical physiological signals with no data loss over eight consecutive hours in daily life, even with exaggerated body movements.