Intramuscular Near-Infrared Spectroscopy for Muscle Flap Monitoring in a Porcine Model.
Intramuscular Near-Infrared Spectroscopy for Muscle Flap Monitoring in a Porcine Model.
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DOI：
10.1055/s-0041-1732361
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发表时间：
2022-05
影响因子：
2.1
通讯作者：
Pet, Mitchell A.
中科院分区：
文献类型：
--
作者：
Bai, Wubin;Guo, Hexia;Ouyang, Wei;Weng, Yang;Wu, Changsheng;Liu, Yihan;Zang, Hao;Jacobson, Lauren;Xu, Yameng;Lu, Di;Hu, Ziying;Li, Shuo;Arafa, Hany M.;Yang, Hany M.;Westman, Amanda M.;MacEwan, Matthew R.;Rogers, John A.;Pet, Mitchell A.
目前的近红外光谱（NIRS）为基础的系统，用于连续皮瓣监测是有限的皮瓣进行皮肤桨。因此，这种有用且可靠的技术以前并不适用于仅肌肉的自由皮瓣，而其他具有很大局限性的模式仍在继续使用。我们提出了第一个近红外探针，它允许连续监测局部组织氧饱和度（StO2）直接在肌肉组织的物质。该探头具有柔性、亚厘米级、防水、生物相容性，并配有可吸收倒钩，便于临时自动稳定，随后易于无创取出。在动脉和静脉闭塞的猪腹直肌肌皮瓣模型中，将该新型器械与ViOptix T.Ox监测器进行了比较。在这些实验中，T.Ox装置被固定到皮肤桨，而新型探针在相同皮瓣的肌肉成分内。肌内NIRS器械和皮肤安装ViOptix T.Ox器械在整个血管夹闭事件中产生非常相似的StO2描记，在血管夹闭和释放时发生明显的平行变化。描述新型肌内NIRS和T.Ox装置之间的对应关系的零滞后下的归一化互相关>0.99。这种新颖的肌内近红外光谱探头可连续监测肌瓣内的氧饱和度。本实验证明了这种肌内近红外光谱探针用于仅肌肉游离皮瓣监测任务的潜在适用性，其中近红外光谱以前不适用。临床环境中的测试对于评估耐久性和可靠性是必要的。
Current near-infrared spectroscopy (NIRS)-based systems for continuous flap monitoring are limited to flaps which carry a cutaneous paddle. As such, this useful and reliable technology has not previously been applicable to muscle-only free flaps where other modalities with substantial limitations continue to be utilized. We present the first NIRS probe which allows continuous monitoring of local tissue oxygen saturation (StO2) directly within the substance of muscle tissue. This probe is flexible, subcentimeter in scale, waterproof, biocompatible, and is fitted with resorbable barbs which facilitate temporary autostabilization followed by easy atraumatic removal. This novel device was compared with a ViOptix T.Ox monitor in a porcine rectus abdominus myocutaneous flap model of arterial and venous occlusions. During these experiments, the T.Ox device was affixed to the skin paddle, while the novel probe was within the muscle component of the same flap. The intramuscular NIRS device and skin-mounted ViOptix T.Ox devices produced very similar StO2 tracings throughout the vascular clamping events, with obvious and parallel changes occurring upon vascular clamping and release. The normalized cross-correlation at zero lag describing correspondence between the novel intramuscular NIRS and T.Ox devices was >0.99. This novel intramuscular NIRS probe offers continuous monitoring of oxygen saturation within muscle flaps. This experiment demonstrates the potential suitability of this intramuscular NIRS probe for the task of muscle-only free flap monitoring, where NIRS has not previously been applicable. Testing in the clinical environment is necessary to assess durability and reliability.
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DOI：
10.1016/j.bjps.2015.06.006
发表时间：
2015-10-01
影响因子：
2.7
作者：
Bodin, Frederic;Diana, Michele;Bruant-Rodier, Catherine
通讯作者：
Bruant-Rodier, Catherine
影响因子：
3.6
作者：
Chen, Kuang-Te;Mardini, Samir;Wei, Fu-Chan
通讯作者：
Wei, Fu-Chan
影响因子：
3.6
作者：
Koolen, Pieter G. L.;Vargas, Christina R.;Lee, Bernard T.
通讯作者：
Lee, Bernard T.
影响因子：
3.6
作者：
Ferguson, Robert E. H., Jr.;Yu, Peirong
通讯作者：
Yu, Peirong
影响因子：
3.6
作者：
Paydar, Keyianoosh Z.;Hansen, Scott L.;Leon, Pablo
通讯作者：
Leon, Pablo