Effect of neonatal therapy on the motor, cognitive, and behavioral development of infants born preterm: a systematic review.

Effect of neonatal therapy on the motor, cognitive, and behavioral development of infants born preterm: a systematic review.
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DOI:
10.1111/dmcn.14485
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发表时间:
2020-06
影响因子:
3.8
通讯作者:
Dusing SC
Dusing SC
中科院分区:
医学2区
文献类型:
--
作者:
Khurana S;Kane AE;Brown SE;Tarver T;Dusing SC

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综合现有文献并确定从新生儿重症监护病房 (NICU) 开始的新生儿治疗对早产儿运动、认知和行为结果的疗效。数据库中检索了针对胎龄小于 37 周的婴儿进行直接治疗早期干预的随机对照试验或半随机对照试验,这些试验在新生儿重症监护病房 (NICU) 中启动,并由治疗师或家长在治疗师的支持下进行。使用 Cochrane 标准化偏倚风险评估工具评估质量。使用建议分级、评估、制定和评价方法提出建议。十五项研究符合纳入标准。研究分为四个干预类别:(1)家长提供的运动干预(PDMI); (2)治疗师进行的姿势控制干预(TDPCI); (3) 发育护理; (4)口部运动干预。偏倚风险从低(10 项研究)到高(3 项研究)或不明确(2 项研究)。初步支持表明,每日 PDMI 可改善短期甚至长期的运动和认知结果。 TDPCI 可有效促进电机开​​发的短期收益。由新生儿治疗师设计的发育护理计划似乎可以有效改善短期行为,但对于运动和认知结果或长期行为结果尚无定论。关于口腔运动干预措施,没有足够的研究对其改善发育结果的功效充满信心。
To synthesize the existing literature and determine the efficacy of neonatal therapy, starting in the neonatal intensive care unit (NICU), on the motor, cognitive, and behavioral outcomes of infants born preterm. Databases were searched for randomized controlled trials or quasi-randomized controlled trials of direct therapy early intervention for infants with a gestational age of less than 37 weeks, initiated in the NICU and delivered by a therapist or parent with therapist support. Quality was evaluated using the Cochrane standardized risk of bias assessment tool. Recommendations were made using the Grading of Recommendations, Assessment, Development and Evaluations approach. Fifteen studies met the inclusion criteria. Studies were categorized into four intervention categories: (1) parent-delivered motor intervention (PDMI); (2) therapist-delivered postural control intervention (TDPCI); (3) developmental care; and (4) oromotor intervention. Risk of bias varied from low (10 studies) to high (three studies) or was unclear (two studies). Preliminary support indicates that daily PDMI improves motor and cognitive outcomes in the short-term and possibly long-term. TDPCI is effective in promoting short-term gains in motor development. Developmental care programs designed by a neonatal therapist appear to be effective in improving short-term behavior but are inconclusive for motor and cognitive outcomes or long-term behavioral outcomes. Regarding oromotor interventions, there is insufficient research to be confident in their efficacy on improving developmental outcomes.
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