Reconsidering Assumptions of Adolescent and Young Adult Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Dynamics

Reconsidering Assumptions of Adolescent and Young Adult Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Dynamics
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DOI:
10.1093/cid/ciaa1348
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发表时间:
2021-08-01
影响因子:
11.8
通讯作者:
Perlman, David C.
Perlman, David C.
中科院分区:
医学1区
文献类型:
--
作者:
Guilamo-Ramos, Vincent;Benzekri, Adam;Perlman, David C.

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关于青少年和年轻人(AYA)在加速和维持2019冠状病毒病(COVID-19)爆发方面的重要作用的证据越来越多。此外,数据表明,2个已知的因素,有助于高严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的传播-症状前传播和无症状的情况下介绍-可能会放大在AYA。然而,AYA并未被优先列为应对COVID-19大流行的公共卫生关键人群。限制公共卫生对AYA的关注并由AYA的前向传播微不足道的假设驱动的政策决定构成了无意中恢复当地传播动态的风险。从这个角度来看,我们强调了有关AYA传播SARS-CoV-2潜力增加的证据,迄今为止,这些证据很少受到关注,讨论了未来COVID-19控制措施的青少年和年轻人特定考虑因素,并提供了应用程序建议。
Evidence regarding the important role of adolescents and young adults (AYA) in accelerating and sustaining coronavirus disease 2019 (COVID-19) outbreaks is growing. Furthermore, data suggest that 2 known factors that contribute to high severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissibility-presymptomatic transmission and asymptomatic case presentations-may be amplified in AYA. However, AYA have not been prioritized as a key population in the public health response to the COVID-19 pandemic. Policy decisions that limit public health attention to AYA and are driven by the assumption of insignificant forward transmission from AYA pose a risk of inadvertent reinvigoration of local transmission dynamics. In this viewpoint, we highlight evidence regarding the increased potential of AYA to transmit SARS-CoV-2 that, to date, has received little attention, discuss adolescent and young adult-specific considerations for future COVID-19 control measures, and provide applied programmatic suggestions.