Wholegrain foods made from a novel high-amylose barley variety (Himalaya 292) improve indices of bowel health in human subjects
Wholegrain foods made from a novel high-amylose barley variety (Himalaya 292) improve indices of bowel health in human subjects
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DOI：
10.1017/s000711450783902x
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发表时间：
2008-05-01
影响因子：
3.6
通讯作者：
Topping, David L.
中科院分区：
文献类型：
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作者：
Bird, Anthony R.;Vuaran, Michelle S.;Topping, David L.
Himalaya 292（Hordeum vulgare var.喜马拉雅292）是一种新的无壳大麦品种，其缺乏淀粉合成的关键酶活性，从而使谷物含有较少的总淀粉、较多的直链淀粉和较高的总膳食纤维。动物试验表明，喜马拉雅292含有更多的抗性淀粉，对大肠健康生物标志物的积极影响大于可比的全麦谷物产品。本研究比较了由全麦喜马拉雅292制成的食物与由全麦小麦制成的食物对人类受试者肠道健康的粪便生物标志物的影响。17名年龄在31-66岁之间的男性和女性志愿者在随机交叉设计中每天食用相似数量的喜马拉雅292，全麦或精制谷物食品4周。总膳食纤维摄入量从称重的食物记录为45，32和21克/天的喜马拉雅292，全麦和精制谷物时期，分别。与精制谷物食品相比，食用喜马拉雅292食品导致粪便重量增加33%，粪便pH值从7.24降至6.98，粪便浓度增加42%，丁酸盐排泄量增加91%，粪便总SCFA排泄量增加57%，粪便对甲酚浓度降低33%。pH值和丁酸浓度和排泄也显着不同，与全麦小麦。它的结论是，消费的饮食，包括喜马拉雅山292制成的食物提供更多的纤维和改善肠道健康的指数相比，精制谷物食品和某些指数，类似的全麦小麦食品在同等水平的摄入量。
Himalaya 292 (Hordeum vulgare var. Himalaya 292) is a novel hull-less barley variety lacking activity of a key enzyme of starch synthesis giving a grain containing less total starch, more amylose and higher total dietary fibre. Animal trials have shown that Himalaya 292 contains more resistant starch and has greater positive impact on biomarkers of large-bowel health than comparable wholegrain cereal products. The present study compared the effects of foods made from wholegrain Himalaya 292 with those made from wholegrain wheat on faecal biomarkers of bowel health in human subjects. Seventeen male and female volunteers aged 31-66 years consumed similar quantities of Himalaya 292, whole-wheat or refined cereal foods daily for 4 weeks in a randomised cross-over design. Total dietary fibre intakes from weighed food records were 45, 32 and 21 g/d for the Himalaya 292, whole-wheat and refined cereal periods, respectively. Compared with the refined cereal foods, consumption of Himalaya 292 foods resulted in 33 % higher faecal weight, a lowering of faecal pH from 7.24 to 6.98, a 42 % higher faecal concentration and a 91 % higher excretion of butyrate, a 57 % higher faecal total SCFA excretion and a 33 % lower faecal p-cresol concentration. pH and butyrate concentration and excretion were also significantly different compared with wholemeal wheat. It is concluded that consumption of a diet that included foods made from Himalaya 292 supplied more fibre and improved indices of bowel health compared with refined cereal foods and, for some indices, similar wholemeal wheat foods at equivalent levels of intake.