Potential Economic Benefit of Cleft Lip and Palate Repair in Sub-Saharan Africa
Potential Economic Benefit of Cleft Lip and Palate Repair in Sub-Saharan Africa
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DOI：
10.1007/s00268-011-1055-1
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发表时间：
2011-06-01
影响因子：
2.6
通讯作者：
Meara, John G.
中科院分区：
文献类型：
--
作者：
Alkire, Blake;Hughes, Christopher D.;Meara, John G.
越来越多的人接受基本外科护理作为任何正常运作的卫生系统的一个基本要素。为了证明对外科手术的投资是合理的，捐助者需要对治疗外科疾病的经济效益进行估计。本研究以撒哈拉以南非洲地区唇腭裂（CLP）患者为研究对象，采用2008年的人口统计学和经济学数据，建立了唇腭裂手术治疗的经济学模型。2008年继发于CLP的残疾调整生命年总数是根据全球疾病负担项目中公认的唇腭裂发生率和残疾权重计算的。采用人力资本方法和统计生命价值方法，如果在2008年撒哈拉以南非洲的所有CLP事故病例在出生时得到修复，潜在的经济效益介于2.52亿美元至4.41亿美元之间。如果采用VSL，同样的CLP修复术的潜在经济效益将从54亿美元到97亿美元不等。唇裂和腭裂可以对发展中国家的经济健康产生重大影响。进一步的研究应针对量化手术干预的经济效益和量化其成本与经济合理的方法。
Acceptance of basic surgical care as an essential element of any properly functioning health system is growing. To justify investment in surgical interventions, donors require estimates of the economic benefit of treating surgical disease. The present study aimed to establish a methodology for valuing the potential economic benefit of surgical intervention using cleft lip and palate (CLP) in sub-Saharan Africa (SSA) as a model.Economic modeling of cleft lip and cleft palate (CLP) in SSA was performed with retrospective demographic and economic data from 2008. The total number of Disability-Adjusted Life-Years (DALYs) secondary to CLP in 2008 was calculated from accepted clefting incidence rates and disability weights taken from the Global Burden of Disease Project. DALYs were then converted to monetary terms ($US), using both a human capital approach and Value of a Statistical Life (VSL) approach.With the human capital approach, the potential economic benefit if all incident cases of CLP in SSA in 2008 were repaired at birth ranged from $252 million to $441 million. With VSL, the potential economic benefit of the same CLP repair would range from $5.4 billion to $9.7 billion.Cleft lip and cleft palate can have a substantial impact on the economic health of countries in the developing world. Further studies should be directed at quantifying the economic benefit of surgical interventions and quantifying their costs with an economically sound approach.